AI Article Synopsis
- The study examined how different stages of erythrocyte maturity and their quantities affect erythropoiesis in cultured erythroblastic islands.
- It was found that both the amount and the maturity of erythrocytes have a dose-dependent and maturity-dependent inhibitory effect on the formation of erythroblastic islands.
- Additionally, erythrocytes from polycythemic rats were shown to inhibit the maturation and formation of these islands more effectively compared to erythrocytes from normal or anemic rats.
Article Abstract
Comparison of influence of erythrocytes of different stages of maturity, and their amount on erythropoiesis in erythroblastic island culture revealed their dose-dependent and maturity-dependent inhibiting effect on erythropoiesis. Erythrocytes of polycythemic rats inhibit maturing and formation of erythroblastic islands more intensively than erythrocytes of normal on anemic rats.
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