AI Article Synopsis
- A seroepidemiological study in rural Mexico found that age impacts the acquisition of antibodies against the Mexico strain of norovirus, with significantly higher rates in adults (81%) compared to young children (34%).
- Personal and domestic hygiene practices were linked to higher chances of developing antibodies, highlighting the importance of cleanliness and specific household factors.
- Different risk factors were identified for infants (like having dogs in the home) versus older children (such as the mother's agricultural work), suggesting variability in transmission routes for norovirus in different age groups.
Article Abstract
Risk factors associated with transmission of sporadic norovirus (NV; formerly Norwalk-like virus)/Mexico strain were identified in a seroepidemiological study conducted in rural Mexico. Acquisition of Mexico strain IgA antibodies was age-related; 34% of 1-4-year-olds were seropositive, compared with 81% of adults (P<.001). After 12 months, 42% of 1-4-year-olds showed a seroresponse to Mexico strain, compared with 27% of adults (P<.01). Personal and domestic hygiene measures, such as hand washing, general cleanliness of the mother's clothing, and the type of room assigned for cooking were significantly associated with odds of a seroresponse. For infants, having a dog in or near the home was a risk factor for seroresponse (P<.01), whereas, for older children, the mother's involvement in agricultural activities was a risk factor (P<.001). This study provides initial evidence of risk factors associated with sporadic NV infection. Data indicate some similarities to risk factors associated with outbreaks of NV infection.
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| http://dx.doi.org/10.1086/386310 | DOI Listing |
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