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Vertebral augmentation plus pedicle screw fixation versus vertebral augmentation alone in the treatment of osteoporotic thoracolumbar fractures: A Meta-analysis.
World Neurosurg
January 2025
Department of Orthopaedics, Binhai Hospital of Tianjin Medical University General Hospital, Tianjin 300480, China.
Background: This meta-analysis was conducted to compare the efficacy and safety of vertebral augmentation (VA) plus pedicle screw fixation (PSF) with VA for treating osteoporotic thoracolumbar fractures (OTLFs).
Methods: A comprehensive search was conducted in PubMed, Embase, Cochrane Library and China National Knowledge Infrastructure (CNKI) to identify studies comparing PSF+VA with VA for treating OTLF. The primary outcomes were operation time, blood loss, length of stay, visual analogue scale (VAS) score, Oswestry disability index (ODI), Cobb angle, anterior vertebral height (AVH), bone cement leakage, secondary fracture and other adverse events.
Impact of Cement Distribution on the Efficacy of Percutaneous Vertebral Augmentation for Osteoporotic Fractures: Assessment with an MRI-Based Reference Marker.
J Bone Joint Surg Am
January 2025
Department of Orthopaedics, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Background: No studies have evaluated the impact of the cement distribution as classified on the basis of the fracture bone marrow edema area (FBMEA) in magnetic resonance imaging (MRI) on the efficacy of percutaneous vertebral augmentation (PVA) for acute osteoporotic vertebral fractures.
Methods: The clinical data of patients with acute, painful, single-level thoracolumbar osteoporotic fractures were retrospectively analyzed. The bone cement distribution on the postoperative radiograph was divided into 4 types according to the distribution of the FBMEA on the preoperative MRI.
Treatment Strategies for Intermediate Spinal Instability Neoplastic Score (SINS 7-12) Patients: A Systematic Review.
World Neurosurg
December 2024
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA. Electronic address:
Background: The Spinal Instability Neoplastic Score (SINS) is used in determining instability in patients with spinal metastases. Intermediate scores of 7 to 12 suggest possible instability, but there are no clear guidelines to address patients with these scores.
Methods: We searched in PubMed, EMBASE, and Cochrane databases for studies that included patient demographics, tumor histology, surgical or radiotherapy management, and outcomes of patients with intermediate SINS.
The value of semiquantitative analysis of [Tc]MDP SPECT/CT in localizing responsible lesions for suspected fresh osteoporotic vertebral compression fractures in patients with contraindications to MRI.
Clin Physiol Funct Imaging
January 2025
Department of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Purpose: The aim of this study was to evaluate the effectiveness of single-photon emission computed tomography/computed tomography (SPECT/CT) in detecting and localizing the causative vertebra in cases of suspected fresh osteoporotic vertebral compression fractures (OVCFs) in patients with contraindications to MRI.
Methods: A total of 21 patients with severe back pain with 31 suspected OVCF segments and contraindications to MRI were initially identified through radiographs and the back pain-inducing test (BPIT). The responsible vertebral bodies were determined using [Tc]MDP SPECT/CT before percutaneous vertebroplasty (PVP).
Effect of Robot-Assisted Surgery on Clinical Outcomes in Patients with Osteoporotic Vertebral Compression Fractures after Percutaneous Vertebral Augmentation: a Meta-Analysis and a Validation Cohort.
Clin Orthop Surg
December 2024
Department of Spinal Cord, Shandong Wendeng Orthopedic Hospital, Weihai, China.
Background: The objective of this study was to investigate the impact of robot-assisted surgery (RA) on the risk of new vertebral compression fracture (NVCF) and bone cement leakage in patients with osteoporotic vertebral compression fractures (OVCF) after percutaneous vertebral augmentation (PVA), including percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP).
Methods: A meta-analysis was performed to evaluate the clinical outcomes and adverse effects of RA-PVA versus fluoroscopy-assisted (FA)-PVA in patients with OVCF. A validation cohort of 385 patients who underwent PVP or PKP was retrospectively analyzed.
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