In this paper the authors give an overview of two systems (simulation and navigation) which are very important and give support to clinical work by making possible good visualization of the morphology and kinematics of joints. The approach to each patient with changes in the joints is individualized with a computer generated tomographical images which give very precise data which up to now had been inaccessible with clinical testing as the only alternative was the well known invasive diagnostic procedures. The first case concerns the COJOKS simulation system (COmputerized Joint Kinematics Simulation). The second case is of a navigation operative system which has recently been put into use and was developed on the basis of the GPS system (MSNT). This system is used for the precise determination of the bone structure of joints which is, by way of computer transformed into virtual 3D shape. This gives the surgeon all the data necessary during the operative procedure on bone and joint structures.
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Soft Matter
January 2025
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Microfluidic chips are powerful tools for investigating numerous variables including chemical and physical parameters on protein aggregation. This study investigated the aggregation of bovine serum albumin (BSA) in two different systems: a vial-based static system and a microfluidic chip-based dynamic system in which BSA aggregation was induced successfully. BSA aggregation induced in a microfluidic chip on a timescale of seconds enabled a dynamic investigation of the forces driving the aggregation process.
View Article and Find Full Text PDFJ Nurs Adm
January 2025
Author Affiliations: Nursing Research Consultant (Dr Feetham), Nurse Scientist, and Associate Professor, George Washington University School of Medicine, Washington, DC (Dr Kelly), Nursing Research and Development Programs Manager (Dr Engh), Department Nursing Science, Professional Practice Quality, Director Healthcare Consulting CBRE Washington DC (Dr Frame): Chief Nursing Informatics and Education Officer (Dr King), Nurse Practitioner, Psychiatry Consult Liaison Service (Dr Ojini), Division of Emergency Medicine and Trauma Nursing Director (Dr Schultz), Sickle Cell Disease Lead Translation Research Advanced Practice Nurse and Director of the Sickle Cell Disease Transition Clinic, Associate Professor George Washington University (Dr Barbara Speller-Brown), and Simulation Program Manager (Dr Walsh), Children's National Hospital, Washington, DC; and Assistant Professor (Dr Giordano), Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.
Advancing nursing practice to improve care and system outcomes requires doctoral-prepared nurses to conduct programs of research and translate science to practice. The authors describe a Doctoral support group (DSG) at one hospital designed to support nurses considering and navigating doctoral education while continuing as hospital employees. Strategies from 18 years' experience are provided for others to develop and sustain a DSG as part of an environment to support and retain nurses with doctoral degrees.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Robotics, Graduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Four-legged robots are becoming increasingly pivotal in navigating challenging environments, such as construction sites and disaster zones. While substantial progress in robotic mobility has been achieved using reinforcement learning techniques, quadruped animals exhibit superior agility by employing fundamentally different strategies. Bio-inspired controllers have been developed to replicate and understand biological locomotion strategies.
View Article and Find Full Text PDFCogn Neurodyn
December 2025
School of Systems Science, Beijing Normal University, Beijing, 100875 China.
Hippocampus in the mammalian brain supports navigation by building a cognitive map of the environment. However, only a few studies have investigated cognitive maps in large-scale arenas. To reveal the computational mechanisms underlying the formation of cognitive maps in large-scale environments, we propose a neural network model of the entorhinal-hippocampal neural circuit that integrates both spatial and non-spatial information.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2025
Department of Biomedical Engineering, Toronto Metropolitan University, Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada.
The integration of self-expandable nitinol frames with cable-driven parallel mechanisms offers a promising advancement in minimally invasive cardiovascular interventions. This study presents the design, fabrication, and verification of a miniaturized self-expandable nitinol frame to enhance catheter tip steerability and navigation within complex vascular anatomies. The frame is reduced in size for delivery through 7-8 Fr sheaths while accommodating diverse vascular diameters, allowing up to a maximum expansion of 15 mm.
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