Simple discriminations are involved in many functional skills; additionally, they are components of conditional discriminations (identity and arbitrary matching-to-sample), which are involved in a wide array of other important performances. Many individuals with severe disabilities have difficulty acquiring simple discriminations with standard training procedures, such as differential reinforcement. Errorless training methods may be more effective with this population. We used multiple-probe designs to compare two potentially errorless procedures for teaching simple discriminations among three pairs of photos of preferred items (S+) and colored rectangles (S-) to three youths with severe disabilities. In Experiment 1, baseline trials conducted with differential reinforcement yielded near-chance performances on all stimulus sets. A progressive delayed prompt training procedure was then implemented, with stimuli presented flat on the tabletop for one participant and at a 45 degrees angle to the tabletop for the other participants. After 120 teaching trials, accuracy remained near chance. Next, a stimulus control shaping procedure was implemented using an adapted Wisconsin General Test Apparatus (WGTA), with stimuli at a 45 degrees angle to the tabletop. Accuracy increased when this procedure was implemented with each stimulus pair in succession. In Experiment 2, for the participant whose stimuli were presented flat on the tabletop during the progressive delayed prompt training procedure, baseline trials were presented on the WGTA as at the end of Experiment 1, with differential reinforcement; accuracy remained high. On probe trials with stimuli placed flat on the tabletop, accuracy decreased to near-chance levels, indicating that the orientation of the stimulus array was a controlling variable.
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http://dx.doi.org/10.1016/j.ridd.2003.08.002 | DOI Listing |
Autism Res
January 2025
Department of Allied Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Echolalia, the immediate or delayed repetition of speech, is a core diagnostic criterion for autism spectrum disorder. It has been studied for over 50 years and is well-described; however, no consensus on prevalence estimates exists for echolalia's occurrence in autistic youth. The current study sought to (1) describe endorsement of echolalia-related items using parent-, teacher-, and clinician-reports in a well-validated sample of autistic youth and (2) characterize relations between echolalia and other key factors, including age, language ability, and repetitive behaviors.
View Article and Find Full Text PDFTraumatic brain injury (TBI) is a leading cause of mortality and disability worldwide and can lead to secondary sequelae such as increased seizure susceptibility. Emerging work suggests that the thalamus, the relay center of the brain that undergoes secondary damage after cortical TBI, is involved with heightened seizure risks after TBI. TBI also induces the recruitment of peripheral immune cells, including T cells, to the site(s) of injury, but it is unclear how these cells impact neurological sequelae post-TBI.
View Article and Find Full Text PDFDiagn Progn Res
January 2025
Department of Clinical Medicine, Hammel Neurorehabilitation Centre-University Research Clinic, Aarhus University, Voldbyvej 15, 8450, Hammel, Denmark.
Background: The initial theme of the PROGRESS framework for prognosis research is termed overall prognosis research. Its aim is to describe the most likely course of health conditions in the context of current care. These average group-level prognoses may be used to inform patients, health policies, trial designs, or further prognosis research.
View Article and Find Full Text PDFOrphanet J Rare Dis
January 2025
Department of Neurosurgery, Helios Klinikum Erfurt, Erfurt, Germany.
Background: NF2-related schwannomatosis (NF2) is associated with various tumors of the central and peripheral nervous system. There is a wide range of disabilities these patients may suffer from and there is no validated clinical classification for disease severity. We propose a clinical classification consisting of three severity grades to assist in patient management.
View Article and Find Full Text PDFJ Physiol
January 2025
Vascular Physiology Laboratory, Group of Research and Innovation in Vascular Health, Department of Basic Sciences, Faculty of Basic Sciences, Universidad del Bío-Bío, Chillán, Chile.
Ischaemic stroke is a leading cause of death and disability. Circulating extracellular vesicles (EVs) post-stroke may help brain endothelial cells (BECs) counter ischaemic injury. However data on how EVs from ischaemic stroke patients, considering injury severity, affect these cells are limited.
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