A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Detection of hepatitis C virus in the nasal secretions of an intranasal drug-user. | LitMetric

AI Article Synopsis

  • The study explores how hepatitis C virus (HCV) can be transmitted through sharing contaminated items, like straws or spoons, used for snorting cocaine and other drugs.
  • Researchers collected blood and nasal secretion samples from five chronic drug users who had HCV in their blood and analyzed them for the virus.
  • All participants tested positive for HCV in their blood, and the nasal secretions of the individual with the highest viral load were also positive, indicating a risk for HCV transmission via nasal secretions.

Article Abstract

Background: One controversial source of infection for hepatitis C virus (HCV) involves the sharing of contaminated implements, such as straws or spoons, used to nasally inhale cocaine and other powdered drugs. An essential precondition for this mode of transmission is the presence of HCV in the nasal secretions of intranasal drug users.

Methods: Blood and nasal secretion samples were collected from five plasma-positive chronic intranasal drug users and tested for HCV RNA using RT-PCR.

Results: HCV was detected in all five blood samples and in the nasal secretions of the subject with the highest serum viral load.

Conclusions: This study is the first to demonstrate the presence of HCV in nasal secretions. This finding has implications for potential transmission of HCV through contact with contaminated nasal secretions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC421742PMC
http://dx.doi.org/10.1186/1476-0711-3-6DOI Listing

Publication Analysis

Top Keywords

nasal secretions
20
hepatitis virus
8
secretions intranasal
8
presence hcv
8
hcv nasal
8
intranasal drug
8
nasal
6
hcv
6
secretions
5
detection hepatitis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!