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Molecular mechanism of osteoclast differentiation of PBMC in patients with rheumatoid arthritis.
Clin Rheumatol
January 2025
Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou Province, China.
Objective: Rheumatoid arthritis (RA) is an autoimmune condition that causes severe joint deformities and impaired functionality, affecting the well-being and daily life of individuals. Consequently, there is a pressing demand for identifying viable therapeutic targets for treating RA. This study aimed to explore the molecular mechanisms of osteoclast differentiation in PBMC from patients with RA through transcriptome sequencing and bioinformatics analysis.
View Article and Find Full Text PDFAgronomic characteristics, mineral nutrient content, antioxidant capacity, biochemical composition, and fatty acid profile of Iranian pistachio (Pistacia vera L.) cultivars.
BMC Plant Biol
January 2025
Republic of Türkiye, Ministry of Agriculture and Forestry, Hatay Olive Research Institute Directorate, General Directorate of Agricultural Research and Policies, Hassa Station, Hassa, Hatay, 31700, Türkiye.
Background: Pistachio (Pistacia vera L.) nuts are among the most popular nuts. The pistachio cultivars are tolerant to both drought and salinity, which is why they are extensively grown in the arid, saline, and hot regions of the Middle East, Mediterranean countries, and the United States.
View Article and Find Full Text PDFDetermination of genetic diversity in persimmon accessions using morphological and inter simple sequence repeat markers.
Sci Rep
January 2025
Department of Plant Biology, Faculty of AgriSciences, Mendel University in Brno, Zemědělská, 1665/1, 61300, Brno, Czech Republic.
Background: Persimmon (Diospyros kaki L.) belongs to the Ebenaceae family, which includes six genera and about 400 species. This study evaluated the genetic diversity of 100 persimmon accessions from Hatay province, Türkiye using 42 morphological and pomological traits, along with inter simple sequence repeat (ISSR) markers and multivariate analysis.
View Article and Find Full Text PDFAddressing drivers and data gaps in Spain's non-compliance of drinking water quality standards.
Sci Total Environ
January 2025
Departamento de Geodinámica, Estratigrafía y Paleontología, Facultad de Ciencias Geológicas, Universidad Complutense de Madrid, Calle José Antonio Nováis 12, 28040 Madrid, Spain.
In 2021 Spain passed a new law regarding the quality of drinking water, increasing the transparency and introducing a risk assessment approach to the catchment area, which ascribe to the shift in recent years in how drinking water management is understood in the European Union legislation. Good data quality is important to ensure the correct implementation of policies. We used the drinking quality data uploaded to Spain's National Drinking Water Information System to gauge the state of the drinking water reporting in Spain, the differences between rural urban and rural areas in both quality and reporting and identify which variables at catchment level influence the probability of a municipality incurring in drinking water quality non-compliance.
View Article and Find Full Text PDFCoercive measures in disability and mental health care services: Mechanical restraints from a bioethical and legal perspective in Spain.
Int J Law Psychiatry
January 2025
Benito Menni CASM, Spain.
This article explores the use of coercive measures, particularly mechanical and pharmacological restraints, in disability care settings and mental health services from a bioethical perspective, focusing on how these practices impact the human rights of individuals with mental disorder, focusing on how these practices impact the human rights of individuals with mental disorders. A robust bioethical framework is presented, advocating for principles of autonomy, beneficence, non-maleficence, dignity, dialogical justice, distributive justice, and vulnerability. These principles are integrated to reframe interventions and promote respect for patient rights.
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