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J Soc Cardiovasc Angiogr Interv
January 2025
Cardiovascular Institute, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Background: The optimal revascularization strategy for patients with acute coronary syndrome (ACS) and multivessel disease (MVD) remains debated. This study compares the efficacy and safety of different revascularization strategies in these patients.
Methods: We included 20 studies comparing staged, complete, and culprit-only (CO) revascularization strategies in patients with ACS and MVD.
BMC Cardiovasc Disord
February 2025
Department of Cardiology, Clinical Medical College of Shanghai Tenth People's Hospital, Nanjing Medical University, Shanghai, China.
Background: Contrast-induced acute kidney injury (CI-AKI) is a common complication of percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients. Our aim was to assess the lymphocyte to C-reactive protein ratio (LCR) to predict CI-AKI in patients with acute STEMI.
Methods: A total of 777 patients with STEMI undergoing primary PCI were continuously included in this study.
Sci Rep
February 2025
Department of Cardiology, Dongguan People's Hospital (the Tenth Affiliated Hospital of Southern Medical University), Dongguan, 523050, Guangdong, China.
Contrast-induced nephropathy (CIN) is an acute kidney injury manifests within 72 h post-administration of contrast media, excluding other kidney-damage etiologies. Despite the recognition of CIN, the complex interplay among high-risk factors remains poorly understood, and precision in the existing risk stratification models is lacking. This retrospective, observational cohort study included patients who underwent percutaneous coronary intervention (PCI) or computed tomography angiography (CTA) at four hospitals in Guangdong, China, between 2010 and 2018.
View Article and Find Full Text PDFJACC Cardiovasc Interv
February 2025
Hospital Clínico San Carlos IdISCC, CIBER-CV, and Complutense University of Madrid, Madrid, Spain. Electronic address:
Since its inception, percutaneous coronary intervention (PCI) has relied upon vessel opacification with iodinated contrast to plan, guide, and assess the results of the procedure. Yet revisiting this fundamental concept is important in contemporary PCI practice, especially in patients with high-risk clinical or anatomical profiles. In addition to decreasing the probability of acute kidney injury during PCI, limiting the volume of iodinated contrast allows the operator to perform more thorough interventions by relying on intracoronary imaging and physiology, ultimately contributing to more complete revascularization and improving the efficacy and durability of the intervention.
View Article and Find Full Text PDFClin Transl Med
March 2025
Division of Nephrology, Department of Medicine, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Background: Contrast-induced acute kidney injury (CI-AKI) continues to pose a pressing clinical challenge during invasive cardiovascular procedures due to the limited availability of preventative strategies. We aimed to demonstrate that irisin, a myokine induced by exercise, protects against CI-AKI by inhibiting the cGAS-STING inflammatory pathway.
Methods And Results: We explored the relationship between serum irisin levels and CI-AKI incidence in patients administered the contrast media iohexol.
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