Copper(II) acetate promoted oxidative cyclization of arylsulfonyl-o-allylanilines.

Org Lett

Department of Chemistry, Rm. 618 Natural Sciences Complex, University at Buffalo, The State University of New York, Buffalo, New York 14260, USA.

Published: May 2004

Tosyl-o-allylaniline 1 undergoes oxidative cyclization to produce tetracycle 2 upon treatment with Cu(OAc)(2) and Cs(2)CO(3) at 120 degrees C. The scope of the reaction was extended to other N-sulfonylated aromatic systems.

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Source
http://dx.doi.org/10.1021/ol049702+DOI Listing

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