Housekeeping staff join patient-care teams to improve patient care, but the transition can cause problems of its own. Read how one hospital minimized the negative effects and improved staff productivity and patient satisfaction.
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Physicochemical Properties, Antioxidant Activity, and Flavor Profile of Strawberry Fruit-Based Novel Drinking Jelly Made with Seaweed as a Gelling Agent at Varying Concentrations.
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January 2025
Faculty of Innovative Agriculture, Fisheries and Food, Prince of Songkla University, Surat Thani Campus, Makham Tia, Mueang, Surat Thani 84000, Thailand.
(GF) is a red seaweed that is widely found in Southeast Asia and has gained attention for its potential bioactive compounds and versatile applications in food products. This study explored the potential of GF as a natural gelling agent in the development of sustainable strawberry-based drinking jelly. By utilizing GF at varying concentrations (0.
View Article and Find Full Text PDFPreclinical and First-in-Human Study of a Compact Radionuclide Labeled Self-Assembly Nanomedicine for Chemo-Radio-Theranostics of Cancer.
ACS Nano
January 2025
Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, 119074, Singapore.
The emerging combination of chemotherapy and radionuclide therapy has been actively investigated to overcome the limitations of monotherapy and augment therapeutic efficacy. However, it remains a challenge to design a single delivery vehicle that can incorporate chemotherapeutics and radionuclides into a compact structure. Here, a chelator DOTA- or NOTA-modified Evans blue conjugated camptothecin molecule (EB-CPT) nanoprodrug was synthesized, which could self-assemble into nanoparticles due to its inherent amphiphilicity.
View Article and Find Full Text PDFStaudinger Reaction-Responsive Coacervates for Cytosolic Antibody Delivery and TRIM21-Mediated Protein Degradation.
J Am Chem Soc
January 2025
Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR 99999, China.
A low-molecular-weight compound whose structure strikes a fine balance between hydrophobicity and hydrophilicity may form coacervates via liquid-liquid phase separation in an aqueous solution. These coacervates may encapsulate and convoy proteins across the plasma membrane into the cell. However, releasing the cargo from the vehicle to the cytosol is challenging.
View Article and Find Full Text PDFFunctional optimality underpins the repeated evolution of the extreme "saber-tooth" morphology.
Curr Biol
January 2025
School of Biological Sciences, Monash University, Clayton, Melbourne, VIC 3800, Australia; Geosciences, Museums Victoria, Melbourne, VIC 3001, Australia.
"Saber teeth"-elongate, blade-like canines-are a classic example of convergence, having evolved repeatedly throughout mammalian history. Within canine teeth, there is a trade-off between the aspects of shape that improve food fracture and those that increase tooth strength. Optimal morphologies strike a balance between these antagonistic functional criteria.
View Article and Find Full Text PDFThe carbon cost of impaired welfare on sheep farms.
Animal
December 2024
Scotland's Rural College (SRUC), Roslin Institute Building, Easter Bush Campus, Midlothian EH25 9RG, UK.
In the face of global climate threats, farm and land-management decisions must balance climate concerns with profitability, animal welfare, and ecosystem health. However, few comprehensive studies have quantified the relationship between animal welfare and greenhouse gas (GHG) emissions, and no study focuses specifically on sheep farms. The present study aims to quantify the effects of impaired welfare on GHG emissions for common welfare challenges faced in UK lowland (L) and hill (H) sheep farming systems.
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