AI Article Synopsis
- A patient with cartilage hair hypoplasia (CHH) and T cell immunodeficiency excreted a stable recombinant norovirus for 156 days post-bone marrow transplantation.
- The specific norovirus strain detected was identified as ARG320/1999/US-like recombinant norovirus (rGII-3).
- The child showed symptoms during this virus shedding phase, and it remains unclear if the virus was acquired from an external source or if it resulted from in vivo recombination.
Article Abstract
We have demonstrated the long-term excretion of a stable recombinant norovirus in a patient with cartilage hair hypoplasia (CHH), with a T cell immunodeficiency, following bone marrow transplantation (BMT). The patient excreted an ARG320/1999/US-like recombinant norovirus (rGII-3) for 156 days during a period of immune reconstitution. The child was symptomatic during the period of virus shedding. It is not known if the child acquired the recombinant strain or if recombination occurred in vivo.
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| http://dx.doi.org/10.1016/j.jcv.2003.10.007 | DOI Listing |
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