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http://dx.doi.org/10.1097/00043426-200403000-00015DOI Listing

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is an Apicomplexan parasite that infects erythrocytes and causes the tick-transmitted infection, babesiosis. can cause a wide variety of clinical manifestations ranging from asymptomatic to severe infection and death. Some risk factors for severe disease are well-defined, an immune compromised state, age greater than 50, and asplenia.

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Babesiosis is a tick-borne disease caused by an intraerythrocytic parasite known as spp. Its clinical presentation is often nonspecific and can range from asymptomatic to life-threatening, depending on the host's immune status. This myriad of manifestations potentially overlaps with other familiar conditions such as hematologic malignancy.

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Article Synopsis
  • This study investigated Babesia infection in dogs in Mashhad, Iran, focusing on its prevalence and comparing clinical, hematological, and clinicopathological differences between infected and non-infected dogs.
  • The researchers analyzed blood samples from 150 dogs, including owned, stray, and shelter dogs, using microscopy and PCR, finding a higher prevalence via PCR (15.3%) than microscopy (2%).
  • Key findings showed that housing status and age significantly affected infection rates, with infected dogs exhibiting substantially lower hematocrit and RBC counts, alongside severe anemia and other clinical abnormalities in some cases.
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Human babesiosis is an emerging zoonotic disease; diffused especially in some regions of the United States, it has been less frequently observed in other continents, including Europe. Serological surveys suggest that babesiosis could be more frequent than expected in European countries, representing an emerging health-issue and a possible harm, especially in immunocompromised populations. Only one case of human babesiosis has been reported in Italy and data about the diffusion of the pathogen in this country are scant.

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The endangered Eld's deer is a conserved species in Thailand, where tropical parasitic infections are endemic. Although Eld's deer with babesiosis are generally asymptomatic, they can still harbor the parasite and serve as reservoirs for ticks, spreading the infection to healthy animals within the herd. The present study aimed to investigate potential serum proteome biomarkers of Eld's deer with subclinical Babesia bovis infection.

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