AI Article Synopsis
- Peutz-Jeghers syndrome is an inherited condition marked by benign tissue growths (hamartomatous polyps) and skin discoloration, with a higher prevalence in females.
- The majority of the cases studied involved gastrointestinal issues, as this region is commonly affected by the polyps.
- Treatment involves endoscopic removal of polyps, and ongoing monitoring through various medical tests is essential due to an increased risk of cancer associated with the syndrome.*
Article Abstract
Peutz-Jeghers syndrome is an autonomic dominant disease characterized by hamartomatous polyps and mucocutaneous hyperpigmentation. We present 16 cases; females were more affected. The most common presenting complaints were of gastrointestinal tract. All polyps found were hamartomatous with general distribution through gastrointestinal tract. Endoscopic polypectomy should be carried out for treatment. Radiologic, endoscopic and histologic studies should be conducted for long-term follow-up, because of high risk of malignancy.
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