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[Global surgery-Challenges in the treatment of children with cleft lip and palate].
Chirurgie (Heidelb)
January 2025
Klinik für Mund‑, Kiefer- und Plastische Gesichtschirurgie, Zentrum für Zentrum für Lippen-Kiefer-Gaumenspalten und seltene oro-kranio-faziale Fehlbildungen, Universitätsmedizin Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
Background: Cleft lip and palate is the most frequent malformation in humans that requires surgical correction but is not primarily life-threatening. That is why in many economically not very well developed countries, special surgical care, such as for cleft lip and palate, is not guaranteed at all or is not sufficiently guaranteed, so that numerous aid organizations have been founded for over 50 years to provide help by organizing surgical aid missions. Even if this help seems primarily ethically harmless and very laudable, the lack of rules and instructions unfortunately regularly leads to the fact that legal, ethical and even medical treatment standards are often not observed to the detriment of the affected children.
View Article and Find Full Text PDF[Research progress of single-cell RNA sequencing in the immune microenvironment of spinal cord injury].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
December 2024
Anhui Key Laboratory of Tissue Transplantation, Anhui Key Laboratory of Infection and Immunity, Bengbu 233030, China. *Corresponding author, E-mail:
Spinal cord injury (SCI) represents a complex pathophysiological process involving the interaction of multiple cell types. Conventional sequencing methods can only detect the average gene expression level of the damaged local cell populations, which is difficult to reflect its heterogeneity. Therefore, new technologies are needed to reveal the intercellular heterogeneity and the complex intercellular interactions of the damaged lesions.
View Article and Find Full Text PDF[Sorption and Transport of Antibiotics in Manured Upland Agricultural Soils].
Huan Jing Ke Xue
January 2025
State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Sorption and transport are important environmental behaviors of antibiotics in soils and can determine the fate of antibiotics in environments； however, limited relevant studies have been conducted on long-term manured soils. In this study, batch and repacked soil column experiments were conducted to examine the sorption and transport behavior of four veterinary antibiotics, including sulfamethazine （SMT）, florfenicol （FFC）, doxycycline （DOX）, and enrofloxacin （ENR）, in red soils, yellow soils, and calcareous soils with long-term amendment of chicken or pig manure collected in Zhejiang Province. The results showed that the sorption isothermal data of the four target antibiotics all conformed well to the linear and Freundlich models.
View Article and Find Full Text PDF[Surgery of premature infants-Perspectives and limitations].
Chirurgie (Heidelb)
December 2024
Erasmus MC, University Medical Center Rotterdam, Rotterdam, Niederlande.
The continuous improvement in the quality of modern perinatology, sociodemographic changes and the increasing spread of reproductive medicine have resulted in an increasing number of premature infants to be treated. The treatment of preterm infants (< 37th week of pregnancy) and especially extremely premature infants (< 28th week of pregnancy) is challenging due to immature organ development, which differs considerably from that of other age groups. While the fate of premature infants and especially extremely premature infants was unfavorable 100 years ago, the survival of premature infants > 1000 g has now shifted to survival in over 80% of cases [30].
View Article and Find Full Text PDF[Profiles and motivations of women seeking oocyte preservation in France: A two-years' survey].
Gynecol Obstet Fertil Senol
November 2024
Service d'assistance médicale à la procréation (CMCO), hôpitaux universitaires de Strasbourg, rue Louis-Pasteur, 67300 Schiltigheim, France. Electronic address:
Objectives: The new bioethics law of August 2, 2021 allows French women to self-preserve.
Methods: National observational survey over 2 years based on an online questionnaire conducted under the aegis of GEDO (Groupe d'études pour le don d'ovocytes).
Results: The average age of the 282 women who answered the questionnaire, 34.
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