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Emerging Trends in the Management of Gastric Malignancy with Peritoneal Dissemination: Same Disease, Heterogeneous Prognosis.
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First Propaedeutic Department of Surgery, National and Kapodistrian University of Athens, Hippocration General Hospital, 11527 Athens, Greece.
Gastric cancer is a significant global contributor to cancer-related mortality. Stage IV gastric cancer represents a significant percentage of patients in Western countries, with peritoneal dissemination being the most prevalent site. Peritoneal disease comprises two distinct entities, macroscopic (P1) and microscopic (P0CY1), which are associated with poor long-term survival rates.
View Article and Find Full Text PDFControversies in Myopia Control Treatment: What Does it Mean for Future Research?
Am J Ophthalmol
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Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland; Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan Poland. Electronic address:
Purpose: Treatment of myopia has been informed by more than 3 decades of clinical trials and other observations. However, controversies regarding myopia control remain, such as when to stop treatment and what is the long-term efficacy of treatment. This perspective aims to describe clinically relevant and current controversies regarding myopia treatment.
View Article and Find Full Text PDFCould the Effect of Arsenic on the Testis be Reversed after Removing the Insult? A Meta-analysis Study.
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Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brasil.
Arsenic in drinking water has been associated with an increased risk of health concerns. This metalloid is ingested and distributed throughout the body, accumulating in several organs, including the testis. In this organ, arsenic disturbs steroidogenesis and spermatogenesis and affects male fertility.
View Article and Find Full Text PDFSafety of steroids in severe community-acquired pneumonia.
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The systemic use of corticosteroids for patients with severe community-acquired pneumonia (sCAP) remains controversial in clinical practice, particularly in terms of the safety profile of these drugs. This narrative review aims to analyse the available literature data concerning the safety of short-term steroid use in the treatment of sCAP, while also highlighting potential future research directions. Several trials and meta-analyses have evaluated corticosteroid therapy as an adjuvant treatment for sCAP, yielding heterogeneous results regarding its efficacy and safety.
View Article and Find Full Text PDFChanges in the level of unitization moderate the impact of unitization on associative memory and its underlying processing.
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Kangbai Hospital, Hangzhou, Zhengjia, China.
The viewpoint that unitization provides a possibility of increasing the contribution of familiarity to associative memory has been widely accepted, but its effects on associative memory and recollection remain controversial. The current study aims to explain these mixed results by considering a potential moderator: changes in the level of unitization from encoding to retrieval phases. During the encoding phase, participants learned the related and unrelated picture pairs (i.
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