One of the most important tasks faced by highway agencies is identifying road hazards. Agencies use crash statistics to detect road intersections and segments where the frequency of crashes is excessive. With the crash-based method, a dangerous intersection or segment can be pointed out only after a sufficient number of crashes occur. A more proactive method is needed, and motorist complaints may be able to assist agencies in detecting road hazards before crashes occur. This paper investigates the quality of safety information reported by motorists and the effectiveness of hazard identification based on motorist reports, which were collected with an experimental Internet website. It demonstrates that the intersections pointed out by motorists tended to have more crashes than other intersections. The safety information collected through the website was comparable to 2-3 months of crash data. It was concluded that although the Internet-based method could not substitute for the traditional crash-based methods, its joint use with crash statistics might be useful in detecting new hazards where crash data had been collected for a short time.
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Adv Ther
January 2025
Division of General Internal Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Introduction: Daily oral antipsychotics (OAPs) are the mainstay of schizophrenia treatment; however, long-acting injectable antipsychotics (LAIs) are associated with better treatment adherence and improved outcomes.
Methods: This study assessed the real-world comparative effectiveness of LAIs and daily OAPs using claims data from a nationally representative sample of fee-for-service Medicare beneficiaries with schizophrenia. Antipsychotic discontinuation, psychiatric hospitalization, and treatment failure were compared relative to different reference groups using within-individual Cox regression models.
Heliyon
January 2025
Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County, 350, Taiwan.
Introduction: The COVID-19 pandemic has created an urgent demand for research, which has spurred the development of enhanced biosafety protocols in biosafety level (BSL)-3 laboratories to safeguard against the risks associated with handling highly contagious pathogens. Laboratory management failures can pose significant hazards.
Methods: An external system captured images of personnel entering a laboratory, which were then analyzed by an AI-based system to verify their compliance with personal protective equipment (PPE) regulations, thereby introducing an additional layer of protection.
Anal Chem
January 2025
School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China.
The ability to identify unknown risks is the key to improving the level of food safety. However, the conventional nontargeted screening methods for new contaminant identification and risk assessment remain difficult work. Herein, a toxic-oriented screening platform based on high-expression epidermal growth factor receptor HEK293 cell membrane-coated magnetic nanoparticles (EGFR/MNPs) was first used for the discovery of unknown contaminants from food samples.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Neurosurgery, Wuhan Hanyang Hospital, Wuhan, Hubei, China.
This study aimed to investigate the polymorphisms of circadian clock genes and the association of shift work and gene polymorphisms with hypertension in healthcare workers. This study recruited 222 healthcare workers, of whom 76 had primary hypertension (Hyp group) and 146 served as controls (Control group). General information and working hours were collected through questionnaires.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Anesthesiology, Wuhan Hanyang Hospital, Wuhan, Hubei Province, China.
This retrospective study evaluates the clinical impact of perioperative multimodal analgesia in the minimally invasive treatment of severe blunt chest trauma with hemopneumothorax using a thoracoscopic Ni-Ti shape memory embracing plate. A total of 100 patients with severe blunt chest trauma and moderate to severe hemopneumothorax treated at Hanyang Hospital affiliated with Wuhan University of Science and Technology from January 2019 to January 2022 were enrolled. Patients were divided into 2 groups: a control group (50 patients) receiving patient-controlled intravenous analgesia (PCIA), and a study group (50 patients) administered a multimodal analgesia regimen.
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