A preform sleeving technique is demonstrated that allows the fabrication of single-mode polymer microstructured fiber with the smallest core and hole dimensions yet reported to our knowledge. For a fixed triangular hole pattern a range of fibers is produced by adjustment to the operating conditions of the draw tower. Numerical modeling is carried out for one of the fibers produced with a 570-microm external diameter, a core diameter of 2.23 microm, an average hole diameter of 0.53 microm, and an average hole spacing of 1.38 microm. This fiber was shown to be endlessly single mode.
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http://dx.doi.org/10.1364/ol.29.000818 | DOI Listing |
Gland Surg
December 2024
Medical Imaging Department, Affiliated Hospital of Jining Medical University, Jining, China.
Background: Breast cancer is the most common malignant tumor among women, with an increasing incidence each year. The subtypes of human epidermal growth factor receptor 2 (HER2)-negative breast cancer, classified as HER2-low and HER2-zero based on HER2 receptor expression, show differences in clinical characteristics, therapeutic approaches, and prognoses. Distinguishing between these subtypes is clinically valuable as it can impact treatment strategies, including the use of next-generation antibody-drug conjugates (ADCs) targeting HER2-low tumors.
View Article and Find Full Text PDFJ Gastrointest Oncol
December 2024
Medical Physics Unit, Department of Oncology, Faculty of Medicine, McGill University, Montreal, QC, Canada.
Background: Orthotopic models offer a more accurate representation of colorectal cancer (CRC) compared to subcutaneous models. Despite promising results from the reported intra-rectal models, establishing a standardized method for CRC research remains challenging due to model variability, hindering comprehensive studies on CRC pathogenesis and treatment modalities, such as brachytherapy. This study aimed to establish a standardized workflow for an orthotopic intra-rectal animal model to induce the growth of colorectal adenocarcinoma in male and female mice.
View Article and Find Full Text PDFJ Pediatr Endocrinol Metab
January 2025
Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Objectives: To develop a clinical model for predicting the occurrence of Central Precocious Puberty based on the breast development outcomes in chinese girls.
Methods: This is a retrospective study, which included a total of 1,001 girls aged 6-9 years old who visited the outpatient clinic of Beijing Children's Hospital from January 2017 to October 2022 for "breast development". Participants were categorized into pubertal development (PD) cohort and simple premature breast development (PT) according to the criteria, and information was collected and tested for relevant indicators.
Acad Radiol
January 2025
Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China (Y.Z., Y.D., Q.Z., C.Z.). Electronic address:
Rationale And Objectives: This study aimed to develop a predictive model for peritoneal metastasis (PM) in ovarian cancer using a combination radiomics and clinical biomarkers to improve diagnostic accuracy.
Patients And Methods: This retrospective cohort study of 619 ovarian cancer patients involved demographic data, radiomics, O-RADS standardized description, clinical biomarkers, and histological findings. Radiomics features were extracted using 3D Slicer and Pyradiomics, with selective feature extraction using Least Absolute Shrinkage and Selection Operator regression.
Front Vet Sci
December 2024
Department of Anatomy, Faculty of Veterinary Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Introduction: This study aims to quantify the shear wave speed (SWS) and stiffness of the uterine cervix (close to the internal cervical ostium (IOC) which is the cranial portion of cervix and close to the external cervical ostium (EOC) which is the caudal portion of cervix), caruncular areas, and vulvar labia during the postpartum period in healthy Kivircik ewes by using shear-wave elastography. Power Doppler ultrasonography was performed to evaluate the color pixel percentage (CPP) of the caruncles.
Methods: The study included 13 healthy pregnant Kivircik ewes, which were randomly selected.
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