Oxidative, chemical cleavage of the C-P bond in 1-amino-1-(3,4-dihydroxyphenyl)methylphosphonic acid upon the action of NaIO(4) have been the subject of the NMR, EPR and UV-Vis investigations in acidic and basic conditions.

Download full-text PDF

Source
http://dx.doi.org/10.1039/b401633eDOI Listing

Publication Analysis

Top Keywords

cleavage c-p
8
c-p bond
8
1-amino-1-34-dihydroxyphenylmethylphosphonic acid
8
example chemical
4
chemical oxidative
4
oxidative cleavage
4
bond aminophosphonate
4
aminophosphonate chemistry
4
chemistry oxidation
4
oxidation 1-amino-1-34-dihydroxyphenylmethylphosphonic
4

Similar Publications

Mutations Causing X-Linked Recessive Oligodontia with Variable Expression.

Genes (Basel)

December 2024

Department of Pediatric Dentistry & DRI, School of Dentistry, Seoul National University, Seoul 03080, Republic of Korea.

Background/objectives: The ectodysplasin A () gene, a member of the tumor necrosis factor ligand superfamily, is involved in the early epithelial-mesenchymal interaction that regulates ectoderm-derived appendage formation. Numerous studies have shown that mutations in the gene can cause X-linked ectodermal dysplasia (ED) and non-syndromic oligodontia (NSO). Accordingly, this study aimed to identify the causative genetic mutations of the gene.

View Article and Find Full Text PDF

The SARS-CoV-2 papain-like protease PLpro has multiple roles in the viral replication cycle, related to both its polypeptide cleavage function and its ability to antagonize the host immune response. Targeting the PLpro function is recognized as a promising mechanism to modulate viral replication, while supporting host immune responses. However, the development of PLpro-specific inhibitors remains challenging.

View Article and Find Full Text PDF

This study investigates possible pathways arising from the reaction of anionic K[Pt(C^N)(-MeCH)(CN)] complexes, C^N = 2-phenylpyridinate (ppy) and 7,8-benzo[h]quinolate (bzq), with trifluoroacetic acid (TFA), which has been employed in both experimental and computational approaches. Experimental studies clarify that the products of the protonolysis reaction can vary in the K[Pt(C^N)(-MeCH)(CN)] complex depending on the type of the cyclometalated ligand. In the cyclometalated complex with ppy, only one product was observed, resulting from the cleavage of the Pt-C bond of the cyclometalated ligand.

View Article and Find Full Text PDF

C-P Bond Cleavage Through Hydrogenation in Ruthenium Complexes Supported by P,N Ligands.

Inorg Chem

December 2024

Centro de Química Estrutural, Institute of Molecular Sciences, Department of Chemical Engineering Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1000-049 Lisboa, Portugal.

The reactivity of ruthenium hydride complexes supported by 2-((di--butylphosphaneyl)methyl)pyridine, and 2-(di--butylphosphaneyl)pyridine, , was explored. The reaction of {Ru(COD)Cl} with in the presence of base and 10 bar of H gave the expected complex [Ru(L1)(H)Cl], , while the same reaction with gave [Ru(L2)(P(H)Bu)(H)Cl], , that results from the cleavage of a C-P bond. We were able to establish that under the reaction conditions the first species formed is [Ru(L2)(H)Cl], , and that this species decomposes to give complex and is in equilibrium with [Ru(L)Cl], .

View Article and Find Full Text PDF

Rapid Enzymatic Detection of Shiga-Toxin-Producing Using Fluorescence-Labeled Oligonucleotide Substrates.

ACS Infect Dis

December 2024

Department for Infectious Diseases, Division of Enteropathogenic Bacteria and Legionella (FG11), National Reference Centre for Salmonella and other Enteric Bacterial Pathogens, Robert Koch Institute, 38855 Wernigerode, Germany.

Article Synopsis
  • Shiga-toxin-producing E. coli (STEC) are harmful bacteria that can cause severe illnesses like diarrhea and kidney failure, making quick detection crucial but difficult.
  • A new rapid test has been developed using synthetic DNA substrates that produce a fluorescent signal when cleaved by Shiga toxins, allowing for easier identification of STEC.
  • In testing 94 clinical strains, including various STEC serotypes, this assay proved effective for immediate detection of Shiga toxins, potentially enhancing outbreak response and treatment strategies.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!