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http://dx.doi.org/10.1016/s1701-2163(16)30363-2 | DOI Listing |
PLoS One
January 2025
Faculty of Medicine, Division of Population Health and Applied Health Sciences, Clinical Epidemiology Unit, Memorial University, St. John's, Newfoundland and Labrador, Canada.
Background: The number of persons living with multimorbidity-defined as the co-occurrence of at least two chronic conditions in the same individual-is growing globally, especially in developed countries. Traditionally, this increase has been attributed to a growing aging population, sedentary lifestyle, obesity, low socioeconomic status, and individual genetic susceptibility.
Objective: To investigate the prevalence and associated risk factors of the most common multimorbidity (MCM) among Canadian middle-aged and older adults.
Am Heart J
January 2025
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA;. Electronic address:
Background: Risk-benefit tradeoffs between restrictive versus liberal red blood cell transfusion strategies may vary across individuals. This exploratory analysis aimed to derive and evaluate individualized treatment effects of defined transfusion strategies in patients with acute MI and anemia with the goal of minimizing adverse cardiovascular outcomes.
Methods: This study analyzed 3,447 (98.
J Gerontol Soc Work
December 2024
School of Social Work, The University of British Columbia, Vancouver, British Columbia, Canada.
This article is an interview with Professor Deborah O'Connor, a Canadian and internationally well-known scholar in gerontological social work, by her doctoral student Karen Wong before Professor O'Connor's retirement. The interview aims to honor Professor O'Connor's scholarship and contribution to research, practice, policy, and education and to inspire junior researchers and trainees, educators and students, and practitioners in gerontological social work. Professor O'Connor's ground-breaking scholarship is marked by understanding aging and dementia from critical perspectives.
View Article and Find Full Text PDFDose Response
December 2024
Canadian Nuclear Laboratories - Retired, Chalk River, ON, Canada.
The Hiroshima/Nagasaki (H/N) studies by the Radiation Effect Research Foundation have not shown increased leukaemia for acute doses below 200 milli-gray (mGy). By contrast the INWORKS study of leukaemia in workers stated: "This study provides strong evidence of positive associations between protracted low-dose radiation exposure and leukemia". The INWORKS study also claimed increased leukaemia, not including Chronic Lymphocytic Leukaemia, at cumulative occupational doses of less than 100 mGy.
View Article and Find Full Text PDFBMJ Support Palliat Care
December 2024
Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Background: Current proposals for assisted dying in the UK are based on embedding it within a medical, healthcare model. This model is revealing challenges in safeguarding, monitoring and the impact on healthcare.
Objective: To explore if a different model is a safer, pragmatic and realistic alternative.
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