Synthesis and evaluation of oxazaborolidines for antibacterial activity against Streptococcus mutans.

J Med Chem

Department of Medicinal Chemistry and Natural Products, School of Pharmacy, and Faculty of Dentistry, Institute of Dental Sciences, Hebrew University, Jerusalem 91120, Israel.

Published: May 2004

Several representative oxazaborolidines have been synthesized and evaluated against S. mutans for antibacterial activity. This is the first reported antibacterial activity of this class of compounds. The minimal inhibitory concentration values ranged from 0.53 to 6.75 mM.

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Source
http://dx.doi.org/10.1021/jm049899bDOI Listing

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