AI Article Synopsis
- ALS had a high occurrence rate on Guam for years but started to decline after WWII due to westernization.
- The authors of the study link these cultural changes to the decrease in ALS cases.
- They also suggest that these changes may be connected to a rise in diabetes prevalence on the island.
Article Abstract
Amyotrophic lateral sclerosis (ALS) occurred on the island of Guam with unusually high incidence rates for many years but began to disappear with the island's westernization after WW II. The authors document these changes and suggest that they support a hypothesis that cultural changes could be responsible for both the virtual disappearance of this chronic degenerative neurologic disease as well as a concurrent surge in the prevalence of diabetes.
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