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Sexual spores in mushrooms: bioactive compounds, factors and molecular mechanisms of spore formation.
Arch Microbiol
January 2025
Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Throughout the life cycle of mushrooms, countless spores are released from the fruiting bodies. The spores have significant implications in the food and medicine industries due to pharmacological effects attributed to their bioactive ingredients. Moreover, high concentration of mushroom spores can induce extrinsic allergic reactions in mushroom cultivation workers.
View Article and Find Full Text PDFThe dynamics of thrombolysis over time in acute immunologic reactions.
Sci Rep
January 2025
Department of Emergency Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Article Synopsis
- Allergic reactions and angioedema are significant conditions in emergency care, affecting patient management.
- A study evaluated maximum lysis (ML) using thromboelastometry in patients with immunologic reactions, measuring ML at admission and two hours later.
- Results showed that patients still experiencing symptoms after two hours had higher ML than those who were asymptomatic, indicating a potential link between symptom persistence and changes in ML.
Revisiting surfactant protein D: an immune surveillance molecule bridging innate and adaptive immunity.
Front Immunol
January 2025
Department Integrative Agriculture, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, United Arab Emirates.
Surfactant protein D (SP-D) is a C-type lectin that was originally discovered as a lung surfactant associated phospholipid recognising protein. It was originally shown to be of great importance in surfactant turnover and homeostasis in conjunction with another hydrophilic surfactant protein i.e.
View Article and Find Full Text PDFPredictive factors of progression in mild fibrosing interstitial lung disease patients with gender-age-physiology score of 3 or less.
Respir Investig
January 2025
Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.
Article Synopsis
- The study aimed to identify prognostic factors for annual progression in mild fibrosing interstitial lung disease (FILD) using retrospective data and logistic regression analysis.
- Significant factors associated with progression included the diagnosis of specific lung diseases, patient-reported outcomes, changes in lung function tests, and the CT scan's appearance.
- The findings suggest that factors such as exercise-induced hypoxia, radiological patterns, and certain disease diagnoses are key predictors of how FILD may worsen over time.
Hypersensitivity pneumonitis radiologic features in interstitial lung diseases.
Respir Med
January 2025
Center of Excellence for Interstitial Lung Diseases, Tel Aviv Medical Center, Tel Aviv University, Israel; Institute of Pulmonary Medicine, Tel Aviv Medical Center, Tel Aviv University, Israel. Electronic address:
Background: The radiologic criteria of hypersensitivity pneumonitis (HP) guidelines focus on four HP compatible features (HPCF) in high-resolution computed tomography (HRCT): ground glass opacities, mosaic attenuation, air-trapping, and centrilobular nodules. However, evidence to support these criteria are limited.
Methods: Consecutive interstitial lung disease (ILD) patients who underwent HRCT between 2016 and 2021 in three medical centers were included.
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