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Effects of Early-life PFAS Exposure on Child Neurodevelopment: A Review of the Evidence and Research gaps.
Curr Environ Health Rep
January 2025
AJ Drexel Autism Institute, Drexel University, Philadelphia, USA, PA.
Purpose Of Review: Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals with many modern applications, leading to widespread contamination and universal human exposure. PFAS exposure during early life is of particular concern, given susceptibility of the developing fetal and infant brain to toxic exposures. This review aims to synthesize current evidence, discuss methodological challenges, and highlight research gaps to guide future studies on the impact of PFAS on neurodevelopment.
View Article and Find Full Text PDFCutting-edge regeneration technologies for saturated adsorbents: a systematic review on pathways to circular wastewater treatment system.
Environ Monit Assess
January 2025
Department of Chemistry, Chaudhary Bansi Lal University, Bhiwani, Haryana, 127031, India.
Adsorption seemed like an excellent physicochemical process employed for wastewater treatment. In the last few decades, significant improvements have been made in efficiency and economy to remove contaminants from wastewater using several adsorbents. However, less attention was paid to the regeneration of used adsorbents.
View Article and Find Full Text PDFLeukemic cells infiltrate the ovaries without damaging ovarian reserve in an acute myeloid leukemia mouse model.
Endocrinology
January 2025
Olson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Leukemia is one of the most common cancers in prepubertal girls and adolescents, with advances improving survival rates. However, treatments like chemotherapy and radiation are highly gonadotoxic, often causing ovarian insufficiency, early menopause, infertility, and endocrine disorders. Fertility preservation for young female cancer patients, especially prepubertal girls without mature germ cells, relies heavily on ovarian tissue cryopreservation.
View Article and Find Full Text PDFReplacing native grazers with livestock influences arthropods to have implications for ecosystem functions and disease.
Ecol Appl
January 2025
Centre for Ecological Sciences, Indian Institute of Science, Bengaluru, India.
Grazing by large mammalian herbivores influences ecosystem structure and functions through its impacts on vegetation and soil, as well as by the influence on other animals such as arthropods. As livestock progressively replace native grazers around the world, it is pertinent to ask whether they have comparable influence over arthropods, or not. We use a replicated landscape-level, long-term grazer-exclusion experiment (14 years) to address how ground-dwelling arthropods respond to such a change in grazing regime where livestock replace native grazers in the cold deserts of the Trans-Himalayan ecosystem of northern India.
View Article and Find Full Text PDFLamotrigine promotes reentrant ventricular tachycardia in murine hearts.
Epilepsia
January 2025
Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Objective: In 2021, the US Food and Drug Administration issued a safety warning concerning lamotrigine use in patients with underlying cardiac disorders. This warning was based on in vitro data that predicted class Ib antiarrhythmic activity for lamotrigine. Therefore, we investigated the proarrhythmic potential of lamotrigine in the murine heart and compared its effect with flecainide.
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