AI Article Synopsis
- A solid grasp of tear film physiology and associated abnormalities is crucial for veterinarians to effectively diagnose and treat issues related to tear production, whether it's a lack of quantity or quality in the tear film.
- The article covers the development, structure, and functions of various glands involved in tear production, including lacrimal and tarsal glands, as well as goblet cells.
- It also discusses specific treatments for tear film deficiencies, such as lacrimostimulants like cyclosporine and lacrimomimetics, which serve as artificial tear replacements.
Article Abstract
A thorough understanding of tear film physiology and the clinical manifestations of tear film abnormalities enables the veterinarian to diagnose and treat quantitative (decreased aqueous layer) and qualitative (decreased mucin or lipid layers) tear film abnormalities accurately and to monitor the responses to lacrimostimulatory and lacrimomimetic therapy. This article reviews the embryology,anatomy, and physiology of the lacrimal glands; glands of the nictitating membrane; goblet cells; and tarsal glands as well as the pathophysiology of tear film deficiencies. We also review lacrimo-stimulants, including cyclosporine, tacrolimus, sirolimus, pilocar-pine, and lacrimomimetics (tear film replacements).
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| http://dx.doi.org/10.1016/j.cvsm.2003.12.009 | DOI Listing |
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