New imidazole-free H3 antagonists have been found in a series of cinnamic amides of (S)-(aminomethyl)pyrrolidines. The influence of the substituent on the aromatic moiety on the potency and the inhibition of three cytochrome P450 subtypes are also described.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmc.2004.03.021 | DOI Listing |
Publication Analysis
Top Keywords
cinnamic amides
8
amides s-2-aminomethylpyrrolidines
4
s-2-aminomethylpyrrolidines potent
4
potent antagonists
4
antagonists imidazole-free
4
imidazole-free antagonists
4
antagonists series
4
series cinnamic
4
amides s-aminomethylpyrrolidines
4
s-aminomethylpyrrolidines influence
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!