The clinical spectrum of neurosyphilis is large. Serologic tests for syphilis are commonly indicated in diseases involving the central nervous system. The diagnosis of syphilis relies on epidemiological, clinical and biological grounds (cerebrospinal fluid abnormalities and RPR test). The treatment of neurosyphilis is still penicillin G.
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J Dent Sci
January 2025
Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/purpose: launched a call to action for dermatologists in the rise of syphilis. In practice, dermatologists and stomatologists perform early diagnoses of syphilis and refer patients to adequate treatment.
Materials And Methods: This scientometric study aimed to investigate and compare research trends and characteristics of syphilis publications by dermatologists and stomatologists in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
J Community Hosp Intern Med Perspect
November 2024
Department of Medicine, Georgetown University School of Medicine, Washington DC, USA.
Neurosyphilis is a condition characterized by insidious onset of encephalopathy and delirium. The infrequency with which it is encountered makes neurosyphilis a formidable diagnostic challenge. We present a rare case of a 71-year-old male with ischemic cardiomyopathy, chronic obstructive pulmonary disease (COPD), undifferentiated arthritis and alcohol use disorder who was brought to the emergency department after he was found altered, confused, and paranoid.
View Article and Find Full Text PDFJACC Case Rep
January 2025
Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
A 51-year-old man with a history of antibiotic therapy for syphilis 1 month ago presented with syncope. Computed tomography revealed circumferential aortic wall thickening complicating severe stenosis of left main coronary ostium. Abnormalities in serologic and cerebrospinal fluid tests led to the diagnosis of syphilitic aortitis and neurosyphilis.
View Article and Find Full Text PDFJ Infect Dis
January 2025
Department of clinical laboratory, The First Hospital of Jiaxing or The Affiliated Hospital of Jiaxing University, Jiaxing, China.
Cureus
December 2024
Internal Medicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Syphilis, an infection caused by , is well known for its ability to mimic other diseases across various organ systems, complicating timely diagnosis. Ocular syphilis, though rare, is a severe manifestation that can closely resemble other eye conditions, making early identification challenging. When conventional treatments fail to improve symptoms, considering syphilis in the differential diagnosis becomes crucial to avoid further complications.
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