AI Article Synopsis
- The study aimed to investigate the localization of the signaling protein 14-3-3 in the Schistosoma japonicum parasite.* -
- Cercariae were collected from infected snails to infect rabbits, and various life stages of the parasite were analyzed using immunofluorescence staining.* -
- Findings revealed that Sj14-3-3 is primarily located in the tegument, subtegument, muscle, and parenchyma of both adult worms and younger schistosomula, suggesting its importance for future biological studies.*
Article Abstract
Objective: To study the localization of the signaling protein 14-3-3 of Schistosoma japonicum (Sj14-3-3) in the parasite.
Methods: Cercariae were collected from the infected Oncomelania hupensis for the infection of rabbits. Fifteen-day-old schistosomula and adult worms obtained from infected rabbits 15 and 42 days post-infection were used for frozen sections and indirect immunofluorescence staining with monoclonal antibody to rSj14-3-3.
Results: The results showed that the Sj14-3-3 distributed mainly in the tegument, subtegument, muscle, and parenchyma of both adult worms and 15-day-old schistosomula.
Conclusion: The wide distribution and large sites of Sj14-3-3 in the parasite were clearly demonstrated, which established a significant clue for further studies of biologic actions and application of 14-3-3 protein.
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