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κ-Carrageenan tetrasaccharide ameliorates particulate matter-induced defects in skin hydration of human keratinocytes cells and skin barrier disorders.

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College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China; Fujian Provincial Key Laboratory of Food Microbiology and Enzyme Engineering, Xiamen 361021, China. Electronic address:

Urban air pollutants, mainly represented by PM containing organic and inorganic substances, can penetrate the human skin and trigger oxidative stress, potentially causing skin barrier damage and aging. κ-Carrageenan oligosaccharides as degradation products of natural sulfated polysaccharide have a great potential for skin moisturization as well as improving oxidative stress and inflammation. In this study, κ-carrageenan tetrasaccharide was obtained by enzymatic digestion of κ-carrageenan, and its role in alleviating particulate matter-induced inflammatory response in HaCaT keratinocyte cell line and skin barrier dysfunction was evaluated.

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Science and Technology Innovation Center of Smart Water and Resource Environment, Northeastern University, Shenyang 110819, China; School of Resources and Civil Engineering, Northeastern University, Shenyang 110819, China; Liaoning Institute of Technological Innovation in Solid Waste Utilization, Northeastern University, Shenyang 110819, China.

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Effects of Hydration and a Hyaluronic Acid-Containing Lozenge on Voice Parameters in Conjunction With a Vocal Loading Test.

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Division of Phoniatrics and Pediatric Audiology, Department of Otolaryngology, Munich University Hospital and Faculty of Medicine, Munich University (Ludwig-Maximilians-Universität), Germany.

Purpose: This study explores the effects of water intake and a hyaluronic acid (HA)-containing lozenge on acoustic measurements and vocal oscillation patterns investigated after a vocal loading test (VLT).

Method: Ten healthy subjects (five females, five males) read out loud a standardized text for 10 min at a target level of 80 dB(A), measured 30 cm from the mouth, under three conditions but each after fasting for 2 hr: (a) drinking 0.7 l of water, (b) sucking an HA-containing lozenge, and (c) neither of both before the VLT.

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This research investigates the potential of utilizing types of construction waste as partial cement replacements within concrete formulations. Notably, granodiorite and ceramic powders were introduced at varying substitution ratios. The impact of these waste materials on the compressive strength and radiation shielding effectiveness of traditional concrete was evaluated under both ambient and elevated temperature conditions.

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