Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1056/NEJMoa032565 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Overview of Fungi Classified as Risk Group 3 by the Japanese Society for Medical Mycology.
Med Mycol J
December 2024
Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences.
Article Synopsis
- Fungi are classified into four Risk Groups based on their potential to harm humans, with Risk Group 3 indicating significant dangers, including fatalities.
- This review highlights dangerous fungi like Blastomyces dermatitidis and Cladophialophora bantiana, which are known for severe health impacts and high mortality rates due to laboratory-acquired infections.
- Strict biosafety measures are essential in labs handling these fungi due to their associated risks and documented cases of infections and deaths.
Canadian laboratory incidents with human pathogens and toxins: An overview of reports, 2016-2022.
Can Commun Dis Rep
May 2024
Regulatory, Operations and Emergency Management Branch, Public Health Agency of Canada, Ottawa, ON.
Background: When the Public Health Agency of Canada's and came into force, the reporting of laboratory incidents to the Laboratory Incident Notification Canada (LINC) surveillance system became mandatory. This report summarizes the laboratory exposure and non-exposure data reported from 2016 to 2022, with a particular focus on factors that are not typically presented in LINC's annual report.
Methods: Reported laboratory incidents from 2016 to 2022 were analyzed.
Whole-genome sequences from wild-type and laboratory-evolved strains define the alleleome and establish its hallmarks.
Proc Natl Acad Sci U S A
April 2023
Department of Bioengineering, University of California, San Diego, La Jolla, CA 92101.
The genomic diversity across strains of a species forms the genetic basis for differences in their behavior. A large-scale assessment of sequence variation has been made possible by the growing availability of strain-specific whole-genome sequences (WGS) and with the advent of large-scale databases of laboratory-acquired mutations. We define the "alleleome" through a genome-scale assessment of amino acid (AA) sequence diversity in open reading frames across 2,661 WGS from wild-type strains.
View Article and Find Full Text PDFAerosol formation during processing of potentially infectious samples on Roche immunochemistry analyzers (cobas e analyzers) and in an end-to-end laboratory workflow to model SARS-CoV-2 infection risk for laboratory operators.
Front Public Health
December 2022
Roche Diagnostics GmbH, Penzberg, Germany.
Objectives: To assess aerosol formation during processing of model samples in a simulated real-world laboratory setting, then apply these findings to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to assess the risk of infection to laboratory operators.
Design: This study assessed aerosol formation when using cobas e analyzers only and in an end-to-end laboratory workflow. Recombinant hepatitis B surface antigen (HBsAg) was used as a surrogate marker for infectious SARS-CoV-2 viral particles.
On-demand, remote and lossless manipulation of biofluid droplets.
Mater Horiz
October 2022
Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, 27695, USA.
The recent global outbreaks of epidemics and pandemics have shown us that we are severely under-prepared to cope with infectious agents. Exposure to infectious agents present in biofluids (, blood, saliva, urine ) poses a severe risk to clinical laboratory personnel and healthcare workers, resulting in hundreds of millions of hospital-acquired and laboratory-acquired infections annually. Novel technologies that can minimize human exposure through remote and automated handling of infectious biofluids will mitigate such risk.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!