[Study of injury model in human umbilical vein endothelial cells].

Wei Sheng Yan Jiu

Institute of Health and Enviornment Medicine, Academy of Military Medical Sciences, Tianjin 300050, China.

Published: January 2004

Objective: To establishment the injury by oxidized low density lipoprotein in human umbilical vein endothelial cells.

Methods: Huvecs were exposed to OX-LDL in vitro, then MTT and MDA of Huvecs were measured.

Results: After endothelium cells were exposed to different dose of OX-LDL 24 hours, MTT was decreased significantly, especially in the high dose OX-LDL group.

Conclusion: OX-LDL could lead injury to Huvecs and might be related to atherosclerosis.

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