Factor XIII deficiency: a rare cause of repeated abortions.

Singapore Med J

Department of Obstetrics and Gynaecology, St. John's Medical College Hospital, Bangalore 560034, India.

Published: April 2004

Factor XIII deficiency is a rare cause of early abortion. The obstetrical outcome of four pregnancies in two women with factor XIII deficiency is reported. Both women were treated with substitution therapy using locally-prepared cryoprecipitate. The outcome in these two women demonstrated the need for substitution therapy in early pregnancy leading to an increased chance of obstetrical success.

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