Purpose: To elucidate the relationship between ocular dominance and patient satisfaction with monovision induced by intraocular lens implantation.
Setting: Eye Clinic, Kitasato University School of Medicine Hospital, Sagamihara, Kanagawa, Japan.
Methods: The durations of exclusive visibility of dominant- and nondominant-eye targets were measured in 16 patients with successful monovision and 4 patients with unsuccessful monovision to determine the characteristics of ocular dominance. The dominant eye was determined using the hole-in-card test (sighting dominance). The contrast of target in nondominant eye was fixed at 100%; the contrast of target in the dominant eye varied (ie, 100% to 80% to 60% to 40% to 20%) using rectangular gratings of 2 cycles per degree that were 4 degrees in size.
Results: In the successful monovision group, the reversal thresholds (ie, exclusive visibility of the nondominant eye crosses over that of the dominant eye) were displayed only at low decreasing contrast (80% and 60%). However, in the unsuccessful monovision group, the reversal thresholds were at high decreasing contrast (20%) or not at all. The reversal thresholds in patients with unsuccessful monovision were at a significantly lower contrast than in patients with successful monovision (P<.05).
Conclusions: Success and patient satisfaction in monovision patients were significantly influenced by the magnitude of ocular dominance. The balance technique seems to be a good method to evaluate the quantity of ocular dominance and prospectively evaluate the monovision technique.
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http://dx.doi.org/10.1016/j.jcrs.2003.07.013 | DOI Listing |
Mol Psychiatry
January 2025
Department of Bioscience, University of Oslo, Oslo, Norway.
Perineuronal nets (PNNs) are a condensed form of extracellular matrix primarily found around parvalbumin-expressing (PV+) interneurons. The postnatal maturation of PV+ neurons is accompanied with the formation of PNNs and reduced plasticity. Alterations in PNN and PV+ neuron function have been described for mental disorders such as schizophrenia and autism.
View Article and Find Full Text PDFCortical interneurons play an important role in mediating the juvenile critical period for ocular dominance plasticity in the mouse primary visual cortex. Previously, we showed that transplantation of cortical interneurons derived from the medial ganglionic eminence (MGE) opens a robust period of ocular dominance plasticity 33-35 days after transplantation into neonatal host visual cortex. The plasticity can be induced by transplanting either PV or SST MGE-derived cortical interneurons; it requires transplanted interneurons to express the vesicular GABAergic transporter; and it is manifested by changes to the host visual circuit.
View Article and Find Full Text PDFJ Pak Med Assoc
January 2025
Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
The cross-sectional study was planned to compare the amplitude of accommodation and accommodative facility between the dominant and non-dominant eyes in young university students. The sample comprised 70 healthy young adult students at King Saud University, Saudi Arabia, who were aged 19-27 years with a mean of 21.46±1.
View Article and Find Full Text PDFJ Neurosci
January 2025
Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
We employed high-resolution fMRI to distinguish the impacts of anisometropia and strabismus amblyopia on the evoked ocular dominance (OD) response. Sixteen amblyopic participants (8 females) plus 8 individuals with normal vision (1 female), participated in this study for whom, we measured the difference between the response to stimulation of the two eyes, across areas V1-V4.In controls, the evoked OD response formed the expected striped pattern within V1.
View Article and Find Full Text PDFBehav Res Methods
January 2025
CIMeC, Center for Mind/Brain Sciences, The University of Trento, Trento, Italy.
Sighting dominance is an important behavioral property which has been difficult to measure quantitatively with high precision. We developed a measurement method that is grounded in a two-camera model that satisfies these aims. Using a simple alignment task, this method quantifies sighting ocular dominance during binocular viewing, identifying each eye's relative contribution to binocular vision.
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