AI Article Synopsis
- Two children with mental disabilities exhibited symptoms like choreoathetosis, dystonia, and muscle rigidity following severe jaundice after birth.
- Their medical history indicated kernicterus, a condition caused by high bilirubin levels.
- MRI results showed brain abnormalities, particularly increased signal intensity in the globus pallidus and volume loss in the hippocampus, both linked to bilirubin damage.
Article Abstract
Two children with mental retardation, choreoathetosis, dystonia, and muscle rigidity are reported. They had a history of severe hyperbilirubinemia after birth as a result of Rh isoimmunization. The history and clinical picture suggested the diagnosis of kernicterus. The magnetic resonance imaging examination showed a bilateral signal intensity increase in the globus pallidus on T2-weighted images. Additionally, our patients showed symmetric bilateral hyperintensity and volume loss in the hippocampus, which is known to be another characteristic area of bilirubin deposition in kernicterus.
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| http://dx.doi.org/10.1097/00004728-200403000-00018 | DOI Listing |
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