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Differential alterations of structural network in temporal lobe epilepsy with different seizure types are associated with cognitive and psychiatric status.
Epilepsy Behav
December 2024
Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. Electronic address:
Background: The fundamental pathophysiologic understanding of different seizure types in Temporal lobe epilepsy (TLE) remains unclear. This study aimed to assess the distinct alterations of structural network in TLE patients with different seizure types and their relationships with cognitive and psychiatric symptoms.
Methods: Seventy-three patients with unilateral TLE, including 25 with uncontrolled focal to bilateral tonic-clonic seizures (FBTCS), 25 with controlled FBTCS and 23 with focal impaired awareness seizures (FIAS), as well as 26 healthy controls (HC), underwent the diffusion tensor imaging (DTI) scan.
Longitudinal Study of Epibulbar Dermolipomas Over Five-Year Follow-Up: Growth Analysis, Refractive Errors, and Surgical Outcomes.
Ophthalmic Plast Reconstr Surg
December 2024
Hariram Motumal Nasta & Renu Hariram Nasta Ophthalmic Plastic Surgery Services, KAR Campus.
Purpose: To evaluate the growth, management, and outcomes of epibulbar dermolipomas over a 5-year follow-up period.
Methods: This was a retrospective chart review of epibulbar dermolipoma patients with a minimum follow-up of 5 years, which analyzed the changes in size, refractive errors (spherical equivalent), best-corrected visual acuity, histology, and surgical outcomes.
Results: A total of 61 eyes of 53 patients (32 females) with an average presenting age of 4.
Congenitally Missing Lateral Incisors: Prioritizing Space Closure Whenever Feasible.
Cureus
November 2024
Orthodontics and Dentofacial Orthopedics, Private Sector, Riyadh, SAU.
Congenital missing teeth are among the most prevalent dental malformations. Maxillary lateral incisors are particularly prone to agenesis, often missing bilaterally. This condition presented complex challenges for both patients and clinicians.
View Article and Find Full Text PDFSuccessful Multi-Modal Treatment of Uterine Rhabdomyosarcoma.
Urology
December 2024
Children's Hospital of Philadelphia, Division of Urology.
Uterine RMS is exceedingly rare. The treatment strategy has evolved from aggressive local control with upfront surgery followed by radiation to a more conservative approach with chemotherapy followed by additional treatment pending response, which is outlined in a recent consensus statement from the International Soft-Tissue Sarcoma Consortium. We present a case of a 2-year-old with intermediate risk uterine RMS.
View Article and Find Full Text PDFMicrostructural Degeneration of the Corpus Callosum in Parkinson's Disease with Unilateral Onset: A Free-Water Imaging Study.
ACS Chem Neurosci
December 2024
Department of Radiology, The Second Affiliated Hospital, Zhejiang University of Medicine, Hangzhou 310009, China.
Article Synopsis
- Motor symptom laterality in Parkinson's Disease (PD) impacts both motor and nonmotor symptoms, potentially altering patient prognosis, with compensatory mechanisms in the brain's dominant hemisphere playing a key role.
- This study investigated the microstructural changes in the corpus callosum (CC), the brain's main connector between hemispheres, in 201 right-handed PD patients (split between left- and right-onset) compared to 100 healthy controls using advanced imaging techniques.
- Findings revealed reduced free water and fractional anisotropy, along with increased mean diffusivity in the CC of patients with left-side PD onset, highlighting the relationship between brain structure and disease symptoms.
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