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Plant-based diet in hyperkalemic chronic kidney disease patients receiving sodium zirconium cyclosilicate: a feasibility clinical trial.
Am J Clin Nutr
September 2024
Division of Renal Medicine, Baxter Novum, Department of Clinical Science Intervention and Technology. Karolinska Institutet, Solna, Sweden.
Article Synopsis
- Plant-based diets (PBD) can potentially cause high potassium levels in patients with chronic kidney disease (CKD), but this study examined their safety and feasibility in hyperkalemic patients taking sodium zirconium cyclosilicate (SZC).
- The six-week trial involved 26 CKD patients who first followed a low-protein, low-potassium diet and then switched to a PBD, with potassium levels monitored regularly and SZC adjusted accordingly.
- Results showed a decrease in plasma potassium levels initially, stable potassium levels for most patients during the study, improved dietary quality, and better overall satisfaction with renal treatment, without any dangerous fluctuations in potassium levels.
Evaluating the Effectiveness of a Generative Pretrained Transformer-Based Dietary Recommendation System in Managing Potassium Intake for Hemodialysis Patients.
J Ren Nutr
November 2024
Department of Medical Education, Ruijin Hospital Affifiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Objective: Despite adequate dialysis, the prevalence of hyperkalemia in Chinese hemodialysis (HD) patients remains elevated. This study aims to evaluate the effectiveness of a dietary recommendation system driven by generative pretrained transformers (GPTs) in managing potassium levels in HD patients.
Methods: We implemented a bespoke dietary guidance tool utilizing GPT technology.
Response to "Plant-based diets and postprandial hyperkalemia".
Nutr Rev
March 2024
Department of Nephrology, Nutrition and Dialysis, University Claude Bernard Lyon, Hôpital Lyon Sud, Pierre-Benite, France.
Diet therapy for hyperkalemia in people with chronic kidney disease (CKD) has shifted considerably in recent years with the observations that reported potassium intake is weakly, or not at all, associated with plasma potassium levels in this population. One of the lingering debates is whether dietary potassium presents a risk of hyperkalemia in the postprandial state. Although there is general agreement about the need for additional research, the commentary by Varshney et al contends that the available research sufficiently demonstrates that high-potassium plant foods do not pose a risk of postprandial hyperkalemia.
View Article and Find Full Text PDFAdvanced chronic kidney disease with life-threatening hypokalemia due to undiagnosed Gitelman syndrome.
Clin Nephrol Case Stud
February 2023
Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
We report a case of a 58-year-old woman presenting with symptoms of oliguria, fatigue, anorexia, constipation, hypovolemic signs, and laboratory tests showing severe hypokalemia (1.7 mEq/L), hyponatremia (120 mEq/L), high serum creatinine (SCr, 6.46 mg/dL) and urea (352 mg/dL).
View Article and Find Full Text PDFTiming of dialysis in acute kidney injury using routinely collected data and dynamic treatment regimes.
Crit Care
November 2022
Centre for Justifiable Digital Healthcare, Ghent University Hospital, Ghent, Belgium.
Background And Objectives: Defining the optimal moment to start renal replacement therapy (RRT) in acute kidney injury (AKI) remains challenging. Multiple randomized controlled trials (RCTs) addressed this question whilst using absolute criteria such as pH or serum potassium. However, there is a need for identification of the most optimal cut-offs of these criteria.
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