Objective: To report the experience with OK-432 therapy for lymphangioma in children.
Methods: Retrospective study of 19 children with lymphangioma treated with OK-432 in Ribeirão Preto, state of São Paulo, Brazil, between 1999 and 2003.
Results: All patients presented response to OK-432, 12 had total shrinkage and seven had partial shrinkage varying from 50 to 80%. Patients had fever after injections of OK-432 for 2 to 10 days, no damage to the overlying skin was observed.
Conclusion: OK- 432 is safe, effective and can be used as primary choice of treatment of patients with lymphangiomas because of the excellent response. In these cases surgery should not be necessary. In patients with partial regression new injections of OK-432 must be used to shrink the lesion. Thereby safely surgery could be made.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2223/1156 | DOI Listing |
J Obstet Gynaecol Res
January 2025
Department of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan.
Lymphangioma causing pain during pregnancy is not widely reported, but surgical treatment was performed in each of the reported cases. In our patient, lesions arose in the retroperitoneal cavity and caused intense pain from 17 weeks of gestation. However, surgical treatment was considered difficult because of the location of the lesion.
View Article and Find Full Text PDFBMC Pediatr
January 2025
Department of Pediatrics, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Background: Generalized lymphatic anomaly (GLA) is a rare congenital lymphatic malformation (LM) characterized by multiple infiltrating lymphangiomas in various tissues. Owing to its rarity, information on this disease is obtained mainly through case reports, leading to delayed diagnosis. In this study, we reported a case of generalized lymphatic anomaly in a pediatric patient manifesting as hemorrhagic pleural effusion.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Unidade Local de Saúde de Braga, Braga, PRT.
Lymphangioleiomyomatosis (LAM) is a rare, systemic neoplastic disease that primarily affects women of childbearing age. The disease can arise sporadically or in association with tuberous sclerosis. It is characterized by the proliferation of abnormal smooth muscle-like cells, leading to cystic lung destruction, accumulation of chylous fluid, and development of abdominal tumors.
View Article and Find Full Text PDFPediatr Surg Int
December 2024
Department of Thoracic Surgery, National Center for Children's Health. No.56, Beijing Children's Hospital, Capital Medical University, Nan Li Shi Road, Xi Cheng District, Beijing, 100045, China.
Pan Afr Med J
November 2024
Service de Chirurgie Générale et Oncologique, Centre Hospitalier Universitaire de Beni-Messous, Alger, Algérie.
Intraperitoneal Cystic Lymphangioma (CL) is a rare benign malformative disease of lymphatic origin, with a wide range of clinical symptoms. Diagnosis is based on imaging tests and confirmed by histology. We here report the case of a 54-year-old woman presenting with chronic abdominal pain, with no effect on general condition.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!