Peculiarities of endogenous intoxication in peritonitis in 63 patients with cancer of the stomach and intestine were studied. Three degrees of the intoxication syndrome severity were distinguished: the mild, moderate and severe ones. It is shown that the severity degree of intoxication depends on a phase of peritonitis, stage of tumorous process and state of anti-infective protection of an organism. The steps for surgical detoxication of an organism, depending on severity degree of endogenous intoxication, were defined. Use of a complex of treatment permitted to reduce postoperative lethality of the patients to 33%.

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