Progressive supranuclear palsy syndrome induced by clebopride.

Mov Disord

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clínic de Malalties del Sistema Nerviós (ICMSN), Hospital Clínic Universitari, Barcelona, Spain.

Published: April 2004

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Article Abstract

We report on a patient who presented with a progressive supranuclear palsy (PSP) syndrome while receiving clebopride (CLB), a prokinetic drug with central antidopaminergic properties. The clinical and neurophysiological signs progressively disappeared after CLB withdrawal. To our knowledge, this is the first published PSP-like syndrome attributable to an antidopaminergic drug.

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http://dx.doi.org/10.1002/mds.10692DOI Listing

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