Effect of trematod infection and different concentrations of detergent (20, 50, 80 mg/dm3) onto physical and chemical characteristics of haemolymph of Planorbarius corneus (content of Hb, density, active reaction, amount of Hb per unit of total mass and soft mass of the body) have been investigated. It was noted that all changes of named characteristics caused by detergent were more pronounced in infected mollusks.
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BMC Microbiol
January 2025
Center for Public Health Research, Medical School of Nanjing University, Nanjing, China.
Background: Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), and can cause severe cerebral complications and even fatality in children younger than 5 years old. However, there is no specific medication for EV71 infection in clinical practice. Our previous studies had identified the 6-thioguanine (6-TG), an FDA-approved anticancer drug, as a potential antiviral agent, but its anti-EV71 activity is largely unknown, therefore, we aim to explore the antiviral effect of 6-TG on EV71.
View Article and Find Full Text PDFInfect Control Hosp Epidemiol
January 2025
University of Texas Southwestern Medical Center, O'Donnell School of Public Health, Dallas, TX, USA.
Background: Understanding healthcare personnel's (HCP) contact patterns are important to mitigate healthcare-associated infectious disease transmission. Little is known about how HCP contact patterns change over time or during outbreaks such as the COVID-19 pandemic.
Methods: This study in a large United States healthcare system examined the social contact patterns of HCP via standardized social contact diaries.
Infect Control Hosp Epidemiol
January 2025
Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
Background: Bathing intensive care unit (ICU) patients with chlorhexidine gluconate (CHG) decreases healthcare-associated infections (HAIs). The optimal method of CHG bathing remains undefined.
Methods: Prospective crossover study comparing CHG daily bathing with 2% CHG-impregnated cloths versus 4% CHG solution.
Am J Chin Med
January 2025
School of Pharmacy, Nantong University, 9 Seyuan Road, Nantong 226019, P. R. China.
Ginkgolic acids (GAs) are distinctive secondary metabolites of () primarily found in its leaves and seeds, with the highest concentration located in the exotesta. GAs are classified as long-chain phenolic compounds, and exhibit structural similarities to lignoceric acid. Their structural diversity arises from variations in the length of side chains and their number of double bonds, resulting in six distinct forms within extracts (GBE).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Chemical Engineering, Institute of Polymer Research, Waterloo Institute of Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada. Electronic address:
This study investigated the production and application of lignocellulosic wood vinegar and tar as organic pesticides to combat bacterial canker disease in trees, caused by pathogenic bacteria. Lignocellulosic wood vinegar and tar were produced from various lignocellulosic wastes through pyrolysis at different temperatures, with sawdust at 300 °C, 350 °C, and 400 °C yielding the highest quantity and quality of vinegar. Chemical analysis revealed that the lignocellulosic vinegar contained significant concentrations of acetic acid, methanol, and phenolic compounds, all known for their strong antimicrobial properties.
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