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Analysis of Cancer Stem Cell Markers in Various Histological Subtypes of Adrenocortical Cancer.
Curr Issues Mol Biol
December 2024
Department of Fundamental Pathology, Endocrinology Research Centre, 117036 Moscow, Russia.
Adrenocortical cancer (ACC) is a rare malignant neoplasm originating from the adrenal cortex, presenting limited therapeutic options. An avenue for improving therapeutic efficacy may involve a deeper understanding of the role of adrenocortical stem/progenitor cells in the pathogenesis of this disease. Although existing data suggest stem/progenitor characteristics in certain cell populations within ACC, the challenge remains to identify adrenocortical stem cell markers directly involved in its carcinogenesis.
View Article and Find Full Text PDFTrichoscopic and Clinico-Morphological Evaluation of Tinea Capitis.
Indian Dermatol Online J
April 2024
Department of Dermatology, R.N.T. Medical College, Udaipur, Rajasthan, India.
Article Synopsis
- Tinea capitis (TC) is a prevalent fungal scalp infection mainly affecting children, and trichoscopy offers a noninvasive method for detailed hair examination.
- This study analyzed 140 TC cases over a year, revealing a prevalence rate of 2.69 per thousand and identifying gray patch as the most common variant, with specific trichoscopic features like comma and corkscrew hairs.
- The findings indicate that trichoscopy is effective for quick diagnosis, guiding treatment options, and monitoring treatment success in patients with TC.
Headache in Patients with Sellar Disease: Clinicomorphological Predictors of Headache and the Outcome of Endoscopic Transsphenoidal Surgery.
J Neurol Surg B Skull Base
June 2024
Rhinology and Skull Base Research Group, Applied Medical Research Centre, University of New South Wales, Sydney, Australia.
Sellar pathologies are frequently found on imaging performed to investigate headache. However, both headache and incidental sellar lesions are common. Hence, this study prospectively examined headache prevalence, phenotype, and severity in patients with sellar pathologies and the impact of transsphenoidal surgery on headache.
View Article and Find Full Text PDFThe caspase-8 and procaspase-3 expression in gastric cancer and non-cancer mucosa in relation to clinico-morphological factors and some apoptosis-associated proteins.
Adv Med Sci
March 2023
Department of Human and Medical Genetics, Vilnius University, Vilnius, Lithuania.
Purpose: The aim of the study was to assess the expression of caspase-8 and procaspase-3 proteins in gastric cancer (GC) cells and non-cancerous mucosa in relation to clinical and morphological characteristics of the tumor, postoperative survival as well as other apoptosis-related proteins.
Materials And Methods: The study included 91 GC patients. Expression of the proteins was assessed using immunohistochemical method.
Hepatocellular Carcinoma in Cirrhotic Versus Noncirrhotic Livers: Clinicomorphologic Findings and Prognostic Factors.
Turk J Gastroenterol
March 2023
Department of Gastroenterology, Çukurova University, Adana, Turkey.
Background: Hepatocellular carcinoma mostly develops in a cirrhotic (80%) background. The clinical features of cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma also differ. We aimed to determine the clinicopathologic features, tumor characteristics, treatment options, and overall survival after diagnosing hepatocellular carcinoma and prognostic factors effective on survival of hepatocellular carcinoma developing in cirrhotic and non-cirrhotic conditions.
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