The purpose of this article is to assist nurses in developing a heightened sense of awareness about two often-overlooked types of mood disorders that can have a profound effect on women lives subsyndromal depression and prenatal depression. Subsyndromal depression can no longer be considered "minor" because we now understand the intense negative effect on many women's everyday lives. Screening for this disorder needs to be a routine part of care given to women in most health care environments. Simply helping women with subsyndromal depression to recognize that they may not feel sad or blue will create new opportunities for women to seek care when they are weighed down by symptoms such as sluggishness, foggy thinking, irritability, and food cravings. Nonpharmacologic interventions for subsyndromal depression dovetail with the holistic perspective that is the hallmark of nursing practice. Prenatal depression is a particularly hazardous condition because it isa "silent" form of depression that impacts women and their developing fetuses. It is often difficult to recognize against the backdrop of pregnancy and the tendency to blame emotional changes on pregnancy hormones. Practitioners must be aware of this phenomenon and take it seriously. Prenatal depression can have far-reaching effects if left untreated, impacting the pregnant woman and following that soon-to-be-born child through-out life in various detrimental ways. The pregnant woman who is laboring through the transitions of pregnancy and preparing to transition to the mother of a newborn baby should not be further burdened by the impact of depression.
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http://dx.doi.org/10.1016/j.cnur.2003.11.005 | DOI Listing |
Aging Brain
October 2024
Department of Psychiatry and Behavioral Sciences, Stanford University, USA.
Affective symptoms (i.e., depression, anxiety, and apathy) are the most prevalent subsyndrome of neuropsychiatric symptoms (NPS) in preclinical dementia, such as amnestic mild cognitive impairment (aMCI), and remain a challenge to understand and treat.
View Article and Find Full Text PDFJAMA Psychiatry
January 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Mania/hypomania is the pathognomonic feature of bipolar disorder (BD). As BD is often misdiagnosed as major depressive disorder (MDD), replicable neural markers of mania/hypomania risk are needed for earlier BD diagnosis and pathophysiological treatment development.
Objective: To replicate the previously reported positive association between left ventrolateral prefrontal cortex (vlPFC) activity during reward expectancy (RE) and mania/hypomania risk, to explore the effect of MDD history on this association, and to compare RE-related left vlPFC activity in individuals with and at risk of BD.
Int J Bipolar Disord
November 2024
Department Bipolar Disorders, Altrecht Institute for Mental Health Care, Lange Nieuwstraat 119, Utrecht, 3512 PG, The Netherlands.
Background: Diagnosing bipolar disorder (BD) is challenging, and adequate treatment is of major importance to minimalize the consequences of the illness. Early recognition is one way to address this. Although in clinical research the prodromal phase of BD is gaining interest, the perspective of patients with BD and their caregivers on prodromal symptoms is still lacking.
View Article and Find Full Text PDFJ Affect Disord
December 2024
Department of Neurology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Shandong 264000, China; Yantai Regional Sub Center of National Center for Clinical Medical Research of Neurological Diseases, Shandong, China; Shandong Provincial Key Laboratory of Neuroimmune Interaction and Regulation, China. Electronic address:
Background: Subsyndromal symptomatic depression (SSD) is associated with an elevated risk of cognitive impairment in non-demented older adults. Given that hippocampal and middle temporal gyrus atrophy have been shown to cause SSD, our study aimed to investigate the effect of hippocampal volume on the association between SSD and cognitive impairment.
Methods: 338 non-demented older adults from the ADNI (Alzheimer's Disease Neuroimaging Initiative) cohort who underwent cognitive assessments, questionnaires on depressive symptoms and MRI brain were studied.
Mol Psychiatry
August 2024
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Objective markers of pathophysiological processes underlying lifetime depression and mania/hypomania risk can provide biologically informed targets for novel interventions to help prevent the onset of affective disorders in individuals with subsyndromal symptoms. Greater activity within and functional connectivity (FC) between the central executive network (CEN), supporting emotional regulation (ER) subcomponent processes such as working memory (WM), the default mode network (DMN), supporting self-related information processing, and the salience network (SN), is thought to interfere with cognitive functioning and predispose to depressive disorders. Using an emotional n-back paradigm designed to examine WM and ER capacity, we examined in young adults: (1) relationships among activity and FC in these networks and lifetime depression and mania/hypomania risk; (2) the extent to which these relationships were specific to lifetime depression risk versus lifetime mania/hypomania risk; (3) whether findings in a first, Discovery sample n = 101, 63 female, age = 23.
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