To refer or not to refer: Factors that affect primary care provider referral of patients with cancer to clinical treatment trials.

Background: Despite breakthroughs in experimental cancer treatment, relatively few patients participate in cancer clinical treatment trials (CCTTs). Primary care providers (PCPs) have a strong influence on patients' decisions to participate in a CCTT.

Methods: To determine factors that influence PCP referral of patients to CCTTs, we conducted a descriptive survey of 571 Michigan PCPs.

Results: Attendance at CCTT educational sessions consistently predicted referral. Provider attitudes regarding CCTT perceived knowledge, access, and comfort with responsibilities when patients were in a CCTT also predicted referral.

Conclusions: Findings support allocating funds to provide CCTT education to PCPs to increase numbers of patients willing to participate in CCTTs.