Objective: To evaluate the effect of non-penetrating trabecular surgery (NPTS) with amniotic membrane implant in patients with juvenile glaucoma.
Methods: NPTS with amniotic membrane implant was performed on 32 eyes of 26 patients with juvenile glaucoma aged between 12 approximately 28 years. Intraocular pressure (IOP) was measured pre- and post-operatively by CT-60 non-contact tonometer, intraocular irritations and the bleb appearances were recorded, and the anterior chamber angle of post-operation was observed by gonioscopy. Follow-up was (8.3 +/- 4.2) months after surgery.
Results: IOP of post-operation was significantly decreased (15.7 +/- 3.7) mm Hg (1 mm Hg = 0.133 kPa; t = 4.82, P < 0.01) compared with that of pre-operation (28.6 +/- 7.3) mm Hg. The mean number of drug usage was significantly reduced to 0.8 (t = 128, P < 0.01) after surgery when compared with 3.2 before surgery. On the last visit, the IOP was
Conclusions: NPTS with amniotic membrane implant effectively controls elevated IOP in patients with juvenile glaucoma and reduced the number of anti-glaucoma drug usage without significant post-operative complications. NPTS with amniotic membrane implant is an effective and new method for the treatment of patients with juvenile glaucoma.
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