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A standard procedure for constructing a multi-level social vulnerability index using CLSA and SOS data as working examples.
PLoS One
December 2024
Division of Geriatric Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Background: The construct of social vulnerability attempts to understand social circumstances not merely as a descriptor, but as a predictor of adverse health events. It can be measured by aggregating social deficits in a social vulnerability index (SVI). We describe a standard procedure for constructing a multi-level SVI using two working examples.
View Article and Find Full Text PDFClinical Utility of Various Formulations of Calcipotriene and Betamethasone Dipropionate for the Treatment of Plaque Psoriasis in Patients Aged 12 Years or Older.
Drug Des Devel Ther
December 2024
Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, 35-055, Poland.
Plaque-type psoriasis is a chronic immune-mediated inflammatory skin disease of uncertain etiology, significantly impacting patient well-being. This chronic condition not only contributes to stigmatization and mental health challenges but also poses an independent risk for cardiovascular and other comorbid diseases. Affecting approximately 60 million people globally, psoriasis manifests primarily as mild-to-moderate disease in about 80% of cases, where topical therapy is pivotal.
View Article and Find Full Text PDFDevelopment and validity evidence of an interactive 3D model for thoracic and lumbar spinal fractures pedagogy: a first step of validity study.
Orthop Traumatol Surg Res
December 2024
Hôpital du Kremlin-Bicêtre, Department of Anesthesia, Intensive Care and Perioperative Medicine, Le Kremlin-Bicêtre, France; Simulation Center LabForsSIMS, Bicêtre Medical School, Paris-Saclay University, Le Kremlin-Bicêtre, France.
Background: Thoracic and lumbar spinal fractures are common in trauma care, requiring accurate classification to guide appropriate treatment. While traditional teaching methods use static 2D images, there is a growing need for interactive tools to improve understanding. This study addresses the lack of interactive three-dimensional (3D) models for teaching the AO (Arbeitsgemeinschaft für Osteosynthesefragen) Spine classification for thoracic and lumbar fractures.
View Article and Find Full Text PDFIFOMPT's Educational Standards and International Monitoring: A member survey and review.
Musculoskelet Sci Pract
November 2024
Lakehead University, Northern Ontario, Canada. Electronic address:
Background: The International Federation of Manual and Musculoskeletal Physical Therapists (IFOMPT) membership requires accreditation of countries postgraduate musculoskeletal physiotherapy programmes to meet IFOMPT's Educational Standards through International Monitoring. The Educational Standards and International Monitoring are both being reviewed.
Objectives: To seek insight and feedback from IFOMPT's membership on the Educational Standards and International Monitoring to inform the current review.
Mechanisms of axoneme and centriole elimination in Naegleria gruberi.
EMBO Rep
December 2024
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.
The early branching eukaryote Naegleria gruberi can transform transiently from an amoeboid life form lacking centrioles and flagella to a flagellate life form where these elements are present, followed by reversion to the amoeboid state. The mechanisms imparting elimination of axonemes and centrioles during this reversion process are not known. Here, we uncover that flagella primarily fold onto the cell surface and fuse within milliseconds with the plasma membrane.
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