The purpose of the case study was to define the decision rules for prognosticating, on the basis of laboratory data, the early postoperative clinical course after coronary artery bypass grafting. The method of discriminative analysis was made use in the resolution of tasks. The clinical data was based on the examination results of 508 patients after coronary artery bypass grafting with extracorporeal artificial blood circulation. The results are the detected biochemical and hematological parameters that can be used in prognosticating an early postoperative course and in constructing the linear discriminative functions for all days of the postoperative period, which makes it possible to forecast the risk of lethality with a probability of 85.71%. The above results can be equally used to prognosticate the below: linear discriminative functions for the second postoperative day ensuring the forecast of the risk of inflammatory complication with a probability of 91.67%; and linear discriminative functions for the fifth-sixth postoperative days ensuring the forecast of the lethal outcome with a probability of 83.33%.

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