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Is middle East pain syndrome (MEPS) a variant of fibromyalgia syndrome or a distinct disease?
BMC Rheumatol
January 2025
Rheumatology Department, Al-Azhar University Faculty of Medicine for Girls, 74 Ali Amin St, Nasr City, PO 11727, Cairo, Egypt.
Background: Fibromyalgia Syndrome (FMS) is a chronic disabling musculoskeletal condition of unknown aetiology characterized by generalized musculoskeletal pain, extreme fatigue, mood disturbance, impaired cognition, and lack of refreshing sleep. Middle East pain syndrome (MEPS) is a newly described pollution-induced syndrome of hyperparathyroidism and fibromyalgia mimicking rheumatoid arthritis, characterized by the radiological presence of spur-like excrescences in terminal phalanges. This study aimed to explore the inflammatory nature of Middle East pain and Fibromyalgia syndromes.
View Article and Find Full Text PDFHCV and HBV genotypes: vital in the progression of HCV/ HBV co-infection.
BMC Gastroenterol
January 2025
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, 11433, Saudi Arabia.
Background: Viral hepatitis is the major contributor to liver cirrhosis and hepatocellular carcinoma (HCC). Studies indicated that the co-infection of hepatitis C and hepatitis B virus also prompts liver damage progression. Therefore, in the present study, the prevalence of HCV-HBV co-infection and the impact of HCV-HBV co-infection on the progression of liver damage was evaluated amongst the HCV-infected patients in Pakistan.
View Article and Find Full Text PDFDevelopment of a nomogram for predicting malignancy in BI-RADS 4 breast lesions using contrast-enhanced ultrasound and shear wave elastography parameters.
Sci Rep
January 2025
Department of Radiology, The Second Affiliated Hospital of Wannan Medical College, Kangfu Road, Wuhu, 241006, China.
This study aimed to develop a Least Absolute Shrinkage and Selection Operator (LASSO) logistic regression (LR) model using quantitative imaging features from Shear Wave Elastography (SWE) and Contrast-Enhanced Ultrasound (CEUS) to assess the malignancy risk of BI-RADS 4 breast lesions (BLs). The features predictive of malignancy in the LASSO analysis were used to construct a nomogram. Female patients (n = 111) with BI-RADS 4 BLs detected via routine ultrasound at Ma'anshan People's Hospital underwent SWE, CEUS, and histopathological examinations were enrolled in this study.
View Article and Find Full Text PDFNatural cellulose fibers derived from Dracaena angolensis (Welw. ex Carrière) Byng & Christenh. demonstrate potential as a non-absorbable surgical suture biomaterial.
Sci Rep
January 2025
Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, 10400, Thailand.
Sutures from natural and synthetic materials are utilized to close wounds, stop bleeding, reduce pain and infection, repair cutaneous wounds, minimize scarring, and promote optimal wound healing. We used mechanical and chemical methods to extract cellulose fibers from cylindrical snake grass (Dracaena angolensis) (Welw. ex Carrière) Byng & Christenh.
View Article and Find Full Text PDFSIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.
Sci Rep
January 2025
Department of Spinal Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Inflammation aggravates secondary damage following spinal cord injury (SCI). M1 microglia induce inflammation and exert neurotoxic effects, whereas M2 microglia exert anti-inflammatory and neuroprotective effects. The sine oculis homeobox (SIX) gene family consists of six members, including sine oculis homeobox homolog 1 (SIX1)-SIX6.
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