Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported. We describe the occurrence of LGLPS in a mother and her daughter. HLA typing revealed HLA-DR1 in both patients. Topical tacrolimus was of partial benefit in the daughter.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000076489 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lichen planopilaris: update on diagnosis and treatment.
Semin Cutan Med Surg
March 2009
Centre Sabouraud, Saint Louis Hospital, Paris, France.
Lichen planopilaris (LPP), a follicular form of lichen planus, is a rare inflammatory lymphocyte mediated disorder. Although the physiopathology is unclear, an autoimmune etiology is generally accepted. Women are affected more than men, and the typical age of onset is between 40 and 60 years.
View Article and Find Full Text PDFA 52-year-old man presented for evaluation of patchy alopecia of the scalp, axilla, and groin and of follicular spiny papules. Histopathologic examination showed a dense, follicular, lymphocytic infiltrate and interfollicular interface changes. Lassueur-Graham-Little-Piccardi syndrome is characterized by the triad of scarring, patchy alopecia of the scalp, non-cicatricial alopecia of the axillae and pubis, and a keratotic, follicular eruption.
View Article and Find Full Text PDFFamilial Lassueur-Graham-Little-Piccardi syndrome.
Dermatology
July 2004
Department of Endocrinologic and Metabolic Diseases, University of Genoa, Genoa, Italy.
Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported.
View Article and Find Full Text PDFLassueur-Graham Little-Piccardi (LGLP) syndrome is a distinctive entity associating a scarring patchy alopecia of the scalp, a non-cicatricial axillary and pubic hair loss and a lichenoid follicular eruption. We present a 20-year follow-up of a demonstrative case, which had begun as typical lichen planus. In the literature, the relationship with lichen planus remains unclear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!