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Synergistic Effect of Nickel Hydroxide/Hexagonal Boron Nitride Hybrid: An Efficient Electrocatalyst for Detecting 5-Fluorouracil in Human Blood Serum.
Langmuir
January 2025
Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu India.
5-Fluorouracil (5-Fu) is the third-most often used chemotherapeutic medication and has been scientifically demonstrated to be effective in treating solid tumors, including colorectal, stomach, cutaneous, and breast cancers. When used in excess, it accumulates toxic metabolites, which can have deadly and very harmful effects on people, including neurotoxicity and the induction of morbidity. Therefore, sensitive and rapid analytical techniques for detecting 5-Fu in human blood serum are needed to enhance chemotherapy and forecast the possible adverse effects of 5-Fu residues in the human body.
View Article and Find Full Text PDFThe Ameliorative Effect of Coumarin on Copper Toxicity in : Insights from Growth, Nutrient Uptake, Oxidative Damage, and Photosynthetic Performance.
Plants (Basel)
December 2024
College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Excessive copper (Cu) has become a common physiological disorder restricting the sustainable production of citrus. Coumarin (COU) is a hydroxycinnamic acid that can protect plants from heavy metal toxicity. No data to date are available on the ameliorative effect of COU on plant Cu toxicity.
View Article and Find Full Text PDFStudying the Effect of Reducing Agents on the Properties of Gold Nanoparticles and Their Integration into Hyaluronic Acid Hydrogels.
Molecules
December 2024
Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.
Gold nanoparticles (Au NPs) are a promising target for research due to their small size and the resulting plasmonic properties, which depend, among other things, on the chosen reducer. This is important because removing excess substrate from the reaction mixture is problematic. However, Au NPs are an excellent component of various materials, enriching them with their unique features.
View Article and Find Full Text PDFPerillaldehyde pretreatment alleviates cerebral ischemia-reperfusion injury by improving mitochondrial structure and function via the Nrf2/Keap1/Trx2 axis.
Phytomedicine
December 2024
Department of Neurology, Fujian Medical University Union Hospital, Fuzhou, China; Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, Fuzhou, China; Institute of Clinical Neurology, Fujian Medical University, Fuzhou, China. Electronic address:
Background: Perilladehyde, an extract of perillae in the Labiatae family, can produce significant anti-inflammatory and antioxidant effects. Although literature evidences the favorable effect of perillaldehyde on ischemic stroke, the exact mechanism remains blurred.
Purpose: This study attempted to explore the impact of perillaldehyde on cerebral ischemia-reperfusion injury and the related action mechanism.
Turning the band alignment of carbon dots for visible-light-driven enzymatic asymmetric reduction of aromatic ketone.
Int J Biol Macromol
January 2025
Key Laboratory of Organosilicon Chemistry and Materials Technology, Ministry of Education; College of Materials Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China. Electronic address:
Keto reductases are crucial NAD(P)H-dependent enzymes used for the enantioselective synthesis of alcohols from prochiral ketones. Typically, the NADPH cofactor is regenerated through a second enzyme and/or substrate. However, photocatalytic cofactor regeneration using water as a sacrificial electron and hydrogen donor presents a promising alternative, albeit a challenging one.
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