Silymarin extraction from milk thistle using hot water.

Appl Biochem Biotechnol

Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center, Fayetteville, AR 72701, USA.

Published: July 2004

AI Article Synopsis

  • * Experiments showed that while higher temperatures (above 100°C) reduced extraction time from 200 to 55 minutes, the maximum yield of silymarin compounds and taxifolin didn't increase due to degradation.
  • * At 140°C, significant degradation of unprotected silymarin compounds was noted, and their degradation followed first-order kinetics.

Article Abstract

Hot water is attracting attention as an extraction solvent in the recovery of compounds from plant material as the search for milder and "greener" solvents intensifies. The use of hot water as an extraction solvent for milk thistle at temperatures above 100 degrees C was explored. The maximum extraction yield of each of the silymarin compounds and taxifolin did not increase with temperature, most likely because significant compound degradation occurred. However, the time required for the yields of the compounds to reach their maxima was reduced from 200 to 55 min when the extraction temperature was increased from 100 to 140 degrees C. Severe degradation of unprotected (plant matrix not present) silymarin compounds was observed and first-order degradation kinetics were obtained at 140 degrees C.

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http://dx.doi.org/10.1385/abab:114:1-3:559DOI Listing

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