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Antimicrobial Component Concentrations in the Milk of Peripartum Goats.
Anim Sci J
January 2025
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
The aim of this study was to investigate changes in milk conditions and antimicrobial components in goats during 8 weeks prepartum and 1 week postpartum. Milk was collected weekly from seven prepartum goats 8 weeks before the due day, immediately, and 1 week after parturition. Milk color scores and the concentration of antimicrobial components (cathelicidin-7 and S100A8) were significantly increased prepartum.
View Article and Find Full Text PDFUse of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota.
Sci Rep
January 2025
Department of Veterinary Medicine and Animal Sciences (DIVAS), Università degli Studi di Milano, Lodi, 26900, Italy.
Intramammary dry-off treatment is widely considered an effective method for preventing and curing intramammary infection (IMI) in lactating cows; however, it is not commonly used in small ruminants like goats. Therefore, this study was designed to evaluate the effect of an approved cefazolin-based intramammary treatment on the milk microbiota of Alpine dairy goats during the dry and early lactation periods. Sixty goats were randomly selected based on bacteriological results and randomly allocated into the control group (CG) or the treatment group (TG).
View Article and Find Full Text PDFA recurrence model for non-puerperal mastitis patients based on machine learning.
PLoS One
January 2025
Department of Laboratory Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Objective: Non-puerperal mastitis (NPM) is an inflammatory breast disease affecting women during non-lactation periods, and it is prone to relapse after being cured. Accurate prediction of its recurrence is crucial for personalized adjuvant therapy, and pathological examination is the primary basis for the classification, diagnosis, and confirmation of non-puerperal mastitis. Currently, there is a lack of recurrence models for non-puerperal mastitis.
View Article and Find Full Text PDFLactation, mastitis, and probiotics.
Arch Argent Pediatr
January 2025
Instituto de Lactología Industrial (INLAIN, CONICET-UNL), Faculty of Chemical Engineering, Universidad Nacional del Litoral, Santa Fe, Argentina.
Exclusive breastfeeding during the first six months of life, and prolonged with complementary feeding until 2 years of age or more, is the best nutritional approach in the first stage of life. Mastitis is a pathology that can jeopardize the continuity of breastfeeding. Different methods have been proposed for the prevention and treatment of mastitis, including probiotics.
View Article and Find Full Text PDFA novel broad-spectrum bacteriophage cocktail against methicillin-resistant Staphylococcus aureus: Isolation, characterization, and therapeutic potential in a mastitis mouse model.
PLoS One
January 2025
Department of Pharmaceutical Biotechnology and Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Bovine mastitis is a considerable challenge within the dairy industry, causing significant financial losses and threatening public health. The increased occurrence of methicillin-resistant Staphylococcus aureus (MRSA) has provoked difficulties in managing bovine mastitis. Bacteriophage therapy presents a novel treatment strategy to combat MRSA infections, emerging as a possible substitute for antibiotics.
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